Beta amyloid

Alzheimer Disease is a progressive brain disorder that begins with memory loss. Eventually, this leads to dementia and then death. The disease targets the hippocampus which acts as the memory and intellect database and entangles the neurons which create mixed, lost and delayed signals. The symptoms of this illness are repeated statements, forgets about conversations and events, on a regular basis misplace personal possessions, become lost in familiar places, and over time eventually forget the…

This research suggested that the system called the glympathic system which was named by (Nedergaard ,M.,& Goldman, S.A.(2016). They proved that beta-amyloid were disposed of during the sleep cycle at a much faster rate than when the body was active during the wake cycle. While the body is in the sleep cycle mode, the movement of fluids from cell to cell in the brain is being controlled and the process of disposing harmful proteins are properly channeling through the synapse however if the…

hypothesized that due to the third copy of chromosome 21 in all cells particularly the amyloid precursor protein (APP) could be part of the connection to Alzheimer’s disease being so prevalent in individuals with Down syndrome even though scientists are not clear on all of the functions of APP. It is noted in an article on the Alzheimer’s Association website “One of the brain’s APP processing pathways produces beta-amyloid, a fragment that’s the chief component of plaques and a prime suspect in…

The lay people associate Dementia with memory loss, but it’s just not that simple. Dementia is a gradual disease with many other characteristics, such as, loss of attention, orientation, language, judgement, and reasoning (Lewis, Dirksen, Heitkemper, Bucher, & Harding ). “Personality changes and behavioral problems such as agitation, delusions, and hallucinations may occur” (Lewis, Dirksen, Heitkemper, Bucher, & Harding). All of the issues that come with Dementia affect the entire person’s…

Cerebrospinal fluid Cerebrospinal fluid is important to our body because it can help brain distribute the impact when a head gets injury so that it acts like a cushion, dulling the force. Cerebrospinal fluid is one part of the extracellular of the central nervous system and it is a clear, transparent, bodily fluid that occupies the subarachnoid space and the ventricular system around the brain and spinal cord. The Cerebrospinal fluid is produced by choroid plex, which is a structure in…

“I love sleep. My life has a tendency to fall apart when I’m awake, you know?” was ironically observed by Ernest Hemingway. He was notorious for his love of slumber, he thought that the best time to write was in the morning so he would always awake at the break of dawn. He knew first hand the benefits of sleep though sadly most teenagers do not today. A report found an astonishing low amount of sleep in teenagers’ schedule during a time that they learn to balance their academic, social, and…

changes in a woman’s brain after her death. He found out that there was a shrinking in her cortex, more specifically on the memory, language and judgment area. He also discovered an abnormal accumulation of “plaques”, which are abnormal clusters of Beta-amyloid protein, and tangles, that are twisted strands of phosphorylated…

Alzheimer’s is a neurodegenerative disease that causes a steady decline of cognitive ability, behavioural and physical capabilities, which can be linked to characteristic pathophysiological changes in the brain. An epidemiological study have found that Alzheimer’s disease is the prominent cause of all dementia cases, accounting for more than 50% or all reported cases of dementia (Dong et al, 2012). The originating cause of this dreadful disease has been determined to be due to not just one…

these hormones produced by specialized cells (beta cells) is called insulin (a small protein). Insulin aids in the transport of glucose into the cells for use of energy. When too much glucose is present in the blood, the pancreas releases insulin to keep the levels down to a normal range. Without insulin the glucose level rises and many complications can arise from this. The medical condition where insulin is not produced, produced to a minimum, or…

Researchers have found that beta-amyloid is the “chief component of plaques” regarding the disease (Alzheimer’s Association, 2016). After identifying this amino acid as being a key component to Alzheimer’s disease, researchers were also able to identify what kind of future drug could help with cognitive impairment. The drug that is undergoing further research as a cure for Alzheimer’s disease is solanezumab. Solanezumab is a “monoclonal antibody designed to lower the level of beta-amyloid in…