BEMA film was designed to rapidly deliver a drug across the mucosa when fast onset of effect is required and to formulate drugs with poor oral bioavilability[1] Buprenorphine has very poor oral bioavailability(~10%) due to extensive first pass metabolism[3] and hence cannot be formulated as an oral tablet. IM, IV, suppository, transdermal, sublingual and buccal administration routs all bypass first pass metabolism and hence increase the bioavailability however IM, IV or suppositories would be…
Introduction How might a person feel if diagnosed with Urinary incontinence? When people hear the term “urinary incontinence” they may want to run because it’s an embarrassing thing to NOT be able to control your own bladder. It’s embarrassing and down grading. This paper will provide information regarding the different types of urinary incontinence, suggestions on how to manage incontinence and how to approach someone with this diagnosis to hopefully decrease the negative impressions. What…
there were 10,076 deaths due to alcohol related traffic accident (cdc). Also according to the CDC in that same year there were 22,767 deaths due to prescription drug overdoses. Of these overdoses 16,235 were from opioid painkillers and 6,973 were benzodiazepines also known as sedative/muscle relaxants (cdc). Why is it that drunk driving fatalities seem to garner more attention nation wide that prescription drug overdoses do? You would think that the one with the higher death toll would attract…
A urine test is quick and painless, the test uses a person’s urine to test for any illegal drugs, or prescription medications. The urine tests for alcohol, amphetamines, benzodiazepines, marijuana, PCP, and opioids (). Other form of drug testing are hair testing, perspiration testing, saliva testing, and blood testing (). There are two types of urine drug test, they are the immunoassay gas chromatography/mass spectrometry,…
Abreaction by: Kimberly J. Hands are tied, twisted mercilessly. Tighter and tighter, The blood locked out, Cold locked in… (Cohen, Giller & W., 1987). Many people that experience DID become suicidal, not only because of the condition but also due to the constant scrutiny they sometimes receive from the media, family and friends (Cohen, Giller & W., 1987). In 1977, Caroline Sizemore had developed 22 personalities, but only three could exists at any given time- for any other personality to…
This is an 80-year-old female with 01/14/2003 date of injury, who injured her low back and right hip when she fell out of a chair while reaching for a chart DIAGNOSIS: Chronic low back pain with bilateral radiculitis, degenerative disc, status post laminectomy 12/23/15 Progress Report documented that the patient continues to have pain in her lower back and bilateral hip, which radiates down to the foot. There is also radiating pain to the left side of the neck. The lower back and hip pain are…
Based on Trevor’s symptomology, he is currently experiencing neuroleptic malignant syndrome that is an adverse reaction to anti-psychotic medications and anti-depressant medications (Benzer, 256). Trevor is currently unconscious thus; describing an adverse reaction to the medications he currently has taken copious amounts of (Benzer, 256). From a pathophysiological standpoint, there is a decreased amount of dopamine receptors, due to an initial blockade, and a decreased performance from the…
The phone call came in the afternoon, one of twenty or so that day. Marty, a former patient, had died of a heroin overdose. Reportedly, another person was with her when she injected the heroin but ran off when she crashed. A prompt call to 911 or access to a Narcotic Overdose Rescue Kit might have saved her life. Marty was a rebellious teenager, having dropped out of school in the 11th grade. Her parents thought it was just a phase until she overdosed for the first time on heroin. They had been…
Sea world manipulate their customers into thinking that they provide the best care to their orcas, although this has been proven wrong. In recent tests of sea world’s tanks in 2014 it was found that the chlorine solution was “many times stronger than household bleach” and other chemicals were found dissolved in the water where the whales are confined after being caught or bred, which makes their trainers’ eyes burn and forces the trainers to stay out of the water on occasions. This also affects…
It takes longer for patients to recover from petit mal seizures than grand mal seizures d. None of the above 14. Clonazepam is a ________________ and it works by enhancing the action of _______. a. NMDA receptor antagonist, glutamate b. Benzodiazepine, GABA c. Barbiturate, GABA d. NMDA receptor agonist, glutamate 15. Drugs used in Epilepsy have about four basic mechanisms. They include: a. Activation of calcium channels b. Activation sodium channels c. Stimulation of glutamate d…