Base pair

production to decrease substantially in human hepatoma cells (HepG2) (Hreljac et al. 2008). The strongest genotoxic effect occurred when HepG2 cells were specifically exposed to PT, which caused an increase in cellular components in all four DNA damaged base pairs (Hreljac et al. 2008). Additionally, toxicity of this pesticide can inhibit acetylcholine esterase in cells in the nervous system that can result in a decrease in nerve impulses being transmitted (Pope…

The goal of this lab was to conduct the reaction of 2-methyl-2-butanol with HCl to form 2-chloro-2-methylbutane, and to understand Sn1 and Sn2 reactions, in terms of how they are different and why one is more likely to happen over the other. The OH group in 2-methl-2-butanol is attached to a tertiary Carbon, meaning the reaction should occur via Sn1, a two-step reaction, and Cl should replace the OH group, to form a tertiary halide. HCl was added to 2-methyl-2-butanol and then several…

Imagine a world where life threatening diseases are a thing of the past, where child are born without birth defects or serious illness. Imagine a world where parents could choose what their child looks like, or make sure their child is not susceptible to drug addictions, alcoholism, depression or violence. Imagine a world where parents could make their children genius or amazing athletes. Does this idea scare you or make you excited? Through the use of genetic engineering this imagined world…

paternity, and develop the genetic enhancement and cloning of plants and mammals. In 2003, the Human Genome Project was finally able to announce the mapping of an entire Human Genome ( the entire length of human DNA containing more than 3 Billion base pairs) with an accuracy of 99.99 percent.("DNA…

came home from work that day I told her I want to play softball. She was surprised. Mom said “Oh really? “ “Yes really” I said. “Ok I will talk to your dad about it.” I got my way like always. That next day my dad and I went to Hibbits to go buy me a pair of cleats, batting gloves, a glove, and a bat and a helmet that matches. I was so excited to start playing softball. Months passed, August came. That’s when the softball conditioning started for fall ball. A Friday night was our first…

As Plato writes in the dialogue The Republic, the form of the good is responsible for all truth and knowledge in a society. Since Plato and his colleagues have been debating on how a city state should be ruled and the qualifications the ruler should possess, he begins to examine how the form of the good would be useful for a ruler’s education of the rational part of the soul. As Plato has previously stated, the rational part of the soul allows the mind to have knowledge and wisdom while trying…

Migraines (Confirmed on medical certificate): In 2015 Demelsa was working as an au-pair in Australia, when she slipped in a bath and hit the back of her head receiving a concussion. She spent five days in hospital and then returned to New Zealand and was living in Dunedin with friends. This is when Demelsa says her migraines started. Demelsa reports a constant "base pain" which is a 7-8/10. She reports that she is now used to this pain. Three to four times a week she has an increase of…

Specifications and Use Netting Placement There are four 190 foot long nets connected between the two stands. There are two on the sides oriented vertically and connected to the upright supports. These two nets are connected at the bottom just above the bases of the stands and stretch four and half feet up the upright supports (figure 4). Another net runs the length of the longer of the two angled beams and is 12.5 feet in length, while another runs the length of the shorter angled beam at 10.6…

proper treatment and some lifestyle changes, many go on to live normal and healthy lifestyles. The most common cause this deficiency is a single base-pair substitution leading to a glutamate to lysine mutation. The mutation that causes this disease is frameshift and deletion. Frameshift mutation is when their is an addition or deletion of one or more bases to a gene. In this case it is a deletion. This disrupts the reading frame,…

the DNA occurs like this: “Spontaneous deamination of 5-methylcytosinee converts it to thymine. This results in a T:G mismatch. Repair mechanisms then correct it back to the original C:G pair; alternatively, they may substitute G for A, turning the original C:G pair into an T:A pair, effectively changing a base and introducing a mutation.” (Wikipedia, 2018) DNA methylation can be most commonly found in these different sequences: CpG, CHG, or CHH. For mammals though, methylation is only found in…