Autoimmunity

Arthritis is due to autoimmunity, chemotherapy drugs, also called ‘immunosuppressive drugs’, slow down the rapid reproduction of cells and lowers the amount of certain substances produced by those cells, helping people to feel relief from pain. The 3 most common are: Methotrexate…

CRP was identified from patients with acute pneumococcal pneumonia at the Rockefeller Institute for Medical Research (Tillett and Francis, 1930), a name that reflects its reaction with the C-polysaccharide of Pneumococcus. This pentameric protein with MW 118 kDa has five non-covalently bonded and non-glycosylated identical subunits of 206 amino acids each to form a disk-shaped pentagon (Fig. 1). CRP has been proven as an early indicator of infectious or inflammatory conditions as well as a…

The variability of the human gut microbiome and its effect on health Abstract The human gut microbiome consists of a wide range of microbes such as bacteria, fungi and archaea which can be found in the gastrointestinal tract. This gut microbiome can have both beneficial and harmful effects on the host. On one hand, it is involved in processes such as modulation of the immune system and metabolism which are beneficial for the human host. On the other hand, an imbalance in the gut microbiome…

Edible vaccines Abstract Vaccines are widely used in the whole word. The death rate caused by the infectious organisms has been greatly reduced by the use of vaccines. However traditional vaccines have side-effects. Recently a newer approach to overcome the problems of the traditional vaccines has emerged. Edible vaccines can be better alternatives to the traditional vaccines as they can solve all the problems associated with traditional vaccines. For the production of edible vaccines gene of…

This article is about the hypothesized neurological disorder. For other uses, see Panda (disambiguation). PANDAS Streptococcus pyogenes 01.jpg Streptococcus pyogenes (stained red), a common group A streptococcal bacterium. PANDAS is hypothesized to be an autoimmune condition in which the body's own antibodies to streptococci attack the basal ganglion cells of the brain, by a concept known as molecular mimicry. Classification and external resources Specialty Neurology ICD-9-CM 279.49 Patient UK…

during Seizure-Induced Neuronal Death. The Journal of Neuroscience. 2002;22(19):8458?8465. Komaki S, Kohno M, Matsuura N, Shimadzu M, Adachi N, Hoshide R, Nishiyama S, Matsuda I. The polymorphic 43Thr BCL-2 protein confers relative resistance to autoimmunity: an analytical evaluation. Hum Genet 1998; 103:435?440. Matthew J. Betts and Robert B. Russell. Amino Acid Properties and Consequences of Substitutions. Chapter 14. Bioinformatics for Geneticists. Edited by Michael R. Barnes and Ian C. Gray.…

Autoimmune diseases affect about 50 million of the American population according to the American Autoimmune Statistics. Autoimmune occurs when the immune system can not detect the difference between self and nonself. The human immune system protects the body from foreign virus’ and sends antibodies to kill the unknown virus or intruders. This disease then causes the body to produce antibodies that will attack against the body’s healthy cells. It proceeds to attack itself and it’s healthy body…

Background MS (MS) is an auto immune disease which affects neurons of the central nervous system. A neuron consists of three main parts: an axon, dendrite, and a cell body. The axon is usually myelinated with a substance known as the myelin sheath, created by oligodendrocytes. This consists of twenty percent protein and eighty percent lipid. Each oligodendrocyte creates enough myelin to wrap around several axons. The periodic gaps between the neurons are known as nodes of Ranvier, where the…

Regenerative Medicine Regeneration is not a new idea at all, lizards have been doing it for thousands of years! According to BioMedCentral.com, Aristotle observed a lizard regenerating its tail in 330 BC (Jessop). However, lizards are not the only animals capable of regenerating a lost or damaged appendage; Zebrafish can regrow a lost fin or even a heart, newts and other amphibians can regrow entire limbs, starfish can regrow their entire body from just a single limb, and a deer can…