Autoimmunity

The Paleo diet has become one of the most popular dieting habits in the past decade; it consists of eliminating dairy, processed food, grains, starches, and alcohol from the diet and focusing only on vegetables, fruits, lean meats, seafood, and healthy fats (Wolf, Robb 2016). This diet is derived from scientific studies conducted in order to find what early hominids ate. These studied concluded that humans cannot eat the calorie packed foods available today without consequences (Leonard, William…

Choctaw Native American Indians have a higher prevalence 1 o Other risk factors/associations - Systematic sclerosis is associated with prominent inflammation and autoimmunity; and altered microvascular function DIAGNOSTIC PROCEDURES • Primary diagnostic tools o History and physical examination is suggestive of disease by explicit clinical criteria (i.e., fatigue and arthralgia, 'puffy Angers' and worsening 'heartburn')…

In the last several years, much debate has been raised over the issues of child vaccinations here in the U.S. Various studies have yielded results that support both sides of the debate. At stake, is whether a parent can choose vaccines for their children, a decision that ultimately may protect the child, hurt the child, or possibly put others in the community at risk. Upon thorough factual research, a parent has a more informed to choose which vaccines should be administered to their child…

anemia, and central nervous system involvement.1 Systemic lupus erythematosus (SLE) is an autoimmune disorder that causes chronic inflammation of connective tissues, with multifactorial pathophysiology and heterogeneous clinical manifestations. The autoimmunity is conferred by dysregulation of aspects from both innate and adaptive immunity, which leads to the production of autoantibodies. In SLE the most implicated autoantibodies are those…

Additionally, HLA-B27 positive AS patients expressed the Bcl11b mRNA slightly lower relative to healthy controls (0.40 times down-regulated; P = 0.021, Figure……...). On the other side, HLA-B27-negative AS patients were expressing the Bcl11b mRNA higher, however insignificant (0.51 times up-regulated; P = 0.23, Figure….) than healthy individuals. Methylation level of Bcl11b promoter in PBMCs The methylation status of AS patients and healthy controls has been depicted in Table ……., Figure ……...…

immune system attacking parietal cells of the stomach or vitamin B12-intrinsic factor complexes. Usually the body can differentiate between self and non-self, but in abnormal autoimmune responses, the body attacks its own cells. It is believed that autoimmunity is initiated by activation of antigen-specific T cells. T-cell responses to self-antigens can inflict tissue damage. In the development of pernicious anemia, something triggers B-cells to produce antibodies against parietal cells and…

Regulatory T cells (Treg) maintain self-tolerance and act as an anti-inflammatory. Th17 cells are significant in the development of allergic reactions, NEA, and autoimmunity. Therefore, the elevated expression of IL-17 which is linked to hyper-responsiveness and the disequilibrium between Th17 and Treg cells may be a source for asthma (Furukawa et al. 2015). Antigen presenting cells (APC’s) also play a part in asthma…

Biological functions: The main biological functions for CRP to determine via its ability to identify pathogens and injured cells of the host and mediate their elimination via activating the complement system and phagocytic cells (Brundish and Baddiley,1968 ; Weiser et al., 1997). CRP binds to microorganisms and mediates their killing to more recent observations of protection against bacterial pathogens in CRP transgenic mice. The most significant evidence has supported the notion that CRP plays…

My topic is on Psoriasis. I can remember the first time I seen it I was very young. Big blistery and red patches of scaly skin. I decided to pick this topic because I am interested in working in the dermatology field as a Nurse Practitioner. That means I will be dealing with and seeing all different types of skin problems and issues. My Aunt struggles with this disorder on a daily basis. I was interested in finding out the major impact it has on her life. Psoriasis is a chronic autoimmune…

Whilst we generally hear of the story of how getting pregnant was hard, but staying pregnant was easy, this story is less frequently told, but occurs with approximately 15% of all pregnancies (Serrano and Lima 2006). “At 29 I discovered that, for me, getting pregnant was easy, but staying pregnant was difficult. It took three miscarriages before I finally fell pregnant and stayed that way, eventually leading to my first successful pregnancy at age 34.” It is stories like these that make us…