Autoimmunity

Diabetes mellitus is a growing health issue worldwide. The prevalence of diabetes was estimated to be 382 million people in 2013, and is projected to increase to 592 million by 20351. In 2012, diabetes was directly attributed as the cause of death in 1.5 million individuals, and mortality due to diabetes and associated complications is estimated to be 3.7 million deaths2. This places diabetes mellitus as the 8th leading cause of mortality worldwide according to The World Health Organization…

our skin. Unfortunately, there are people negatively affected by disorders of the immune system either by environmental factors or genetics. There are immunodeficiencies where the body has the inability to defend against attacks. There is also autoimmunity, which is an overreaction of the immune system. A variety of reactions come forth from these immune disorders, but I will focus on the causes and effects of Type 1 Diabetes, allergies, asthma, and celiac disease. Asthma affects over…

donation to ensure complete microbiome recovery and all donors are tested for infectious diseases to prevent transmission. A review of several studies of FMT (Burke & Lamont, 2013) also recommended exclusion of donors with unrelated diseases such as autoimmunity, gastrointestinal disorders, metabolic syndrome and liver disease. In…

Scientists believe several factors such as environmental triggers,viral infections, genetics, and drugs might have an influence on the triggers of autoimmunity. Certain drugs such as methyldopa, nitrofurantoin, and minocycline, among the few, can produce an illness that mimics autoimmune hepatitis. Most cases of this instance improve when the drug is stopped, but in rare cases autoimmune hepatitis may…

INTRODUCTION Systemic Lupus Erythematosus (SLE) is an auto-immune system. Auto mean self. Autoimmune means that our immune system cannot differentiate between foreign invaders and our own healthy body tissues and decide that our healthy cells are foreign substance. Thus, creating autoantibodies which are protein that attack and eventually destroy the healthy tissues. This means that our body ability to prevent and fight against infection are reducing. SLE is more than any connective tissues…

euthanasia due to severe vision loss. Horses are also a good steeping stone between the treatment of uveitis in mice and uveitis in humans. In the future, he hopes that this treatment will be able to be used for patients with severe uveitis due to autoimmunity in order to preserve and restore eyesight. In addition to his uveitis research, Dr. Larkin is also working on projects involving Type 1 Diabetes, Lupus, and Rheumatoid…

Two years ago, my son had just started kindergarten and had a great friend named Jack. One day my son came home from school to tell me that his class had made Jack a get well card because he was in the hospital. I immediately called Jack’s mom, Trasi, to find out what was going on. She told me her son had just been diagnosed with type 1 diabetes. I could tell from the sound of Trasi’s voice that she was having a hard time. I didn’t know very much about type 1 diabetes and couldn’t comprehend…

All humans are designed with two types of immunity; innate and adaptive. The innate immune system can distinguish between different classes of pathogens and recruit the most effective form of adaptive immune response to eliminate them. Adaptive responses are a response that the body adapts to certain injuries or insults. Innate responses are non-specific to the insult. Unlike innate immune responses, the adaptive responses are highly specific to the particular pathogen that induced them (Alberts…

Myasthenia gravis is a neurological disorder that affects the immune system and causes chronic muscle weakness in the skeletal muscles of the human body. The name myasthenia gravis means "grave muscle weakness". A strong indication of myasthenia gravis is muscle weakness that heighten during periods of physical activity and decrease after resting periods. Muscles like those that control eye and eyelid movement, facial expression, eating, speaking, breathing and neck and limb movements can all…

“Iodine Supplementation: Usage ‘with a Grain of Salt.’” International Journal of Endocrinology 2015 (2015): 312305. PMC. Web. 16 May 2018. [5] Negro, Roberto. “Selenium and Thyroid Autoimmunity.” Biologics : Targets & Therapy 2.2 (2008): 265–273. Print. [6] MacFarquhar JK, Broussard DL, Melstrom P, et al. Acute Selenium Toxicity Associated With a Dietary Supplement. Arch Intern Med. 2010;170(3):256–261. doi:10.1001/archinternmed.2009…