Atropine

article A is for Atropine argues that the cause of Dimmesdale's deteriorating health was the result of atropine poisoning. Dr. Khan also claims that this poisoning was accomplished through the agency of a certain physician, claiming that Dimmesdale…

Introduction Background: Atropine as an Alkaloid compound has been in use for ages since the times of the Roman Empire as it was used for local anesthesia. The compound was derived from common organic compounds like Tropane alkaloid that is synthesized by most solanacea family and also from berries of the plant Atropa belladonna. Comprehensive research on the compound Atropine was first carried out by German chemist Friedlueb Ferdinad Runge between 1795-1867, later German based pharmacist…

The hypotheses given were greatly supported during the experiment. Three of the four drugs; Lignocain, Hexamethonium, and Atropine, all showed a decline of inhibition of peristalsis. Nicardipine showed to have complete inhibition of peristalsis. It showed to have a 0 au drug amplitude. There were two standard pressures for this experiment. This was due to the two groups having to compensate for the differences in the two tissues used. Pressures used for Hexamethonium and Nicardipine was 2…

Atropine is classified as a muscarinic anticholinergic parasympatholytic. Atropine comes from a plant called Atropa Belladonna and is one of several drugs classified as a belladonna alkaloids. It selectively blocks muscarinic receptors that inhibit parasympathetic stimulation and it can be absorbed by both enteral and parenteral routes. It is a medication that is distributed in most body tissues. Atropine is a drug that is metabolized in the liver and is normally eliminated in urine in 24 hrs.…

Atropine inhibits the action of acetylcholine at the prostaglandin sites located in the smooth muscle, secretory glands and the CNS. It is used as an antidote for anticholinesterase poisoning and used to increase heart rate and dilate pupils. It is also used to treat hypermotility in the GI tract for issues such as irritable bowel syndrome. Atropine is also used for mydriasis, and decreased secretions from glands. The recommended dose for adults via IM/IV is 0.4-0.6mg 30-60min pre-op to decrease…

The different chemicals that were used in this experiment were Pilocarpine, Atropine Sulfate, Epinephrine, Digitals, Potassium, Sodium, and calcium ion concertation. Pilocarpine stimulates the effect of parasympathetic nerve stimulation by enhancing acetylcholine release. Atropine Sulfate is a drug that blocks the effect of the neurotransmitter acetylcholine which is liberated by the parasympathetic nerve endings. Cardiac muscle and skeletal muscle are both different in functionally and in fine…

Atropine as an inhibitory effect on the neurotransmitter acetylcholine’s action on the cardiac muscle. Atropine release in the body is stimulated by a low heart rate resulting from vagal stimulation and thus functions to increase the heart rate. For this reason, atropine is said to be sympathomimetic in its action (Burggren & Doyle, 1986). These findings are synonymous with the results obtained in the second recording (figure 6) where a combination of atropine and acetylcholine was introduced…

As briefly mentioned before, atropine acts as an antagonist on acetylcholine because its chemical structure is similar to acetylcholine. Thus, structure is an important feature of the atropine molecule that is imperative to understanding its effects on the body. Although today’s chemists know the chemical structure of atropine, the conformational flexibility of the molecule is still poorly understood. A conformation is any three-dimensional arrangement of atoms within a molecule that results…

antagonist into the organ bath made the curves gradually shift to the right in a nearly parallel manner (Fig 1). The higher concentration of Atropine, the more its curve moved to the right of the graph. However, these effects of antagonist did not change the maximum response level. Carbachol binds and activates muscarinic receptors of parasympathetic nervous system like acetylcholine’s effects thus it is listed as a cholinergic agonist. In this simulation experiment, Carbachol was used to exert…

Lomotil is a prescription drug that is often used to treat acute diarrhea. It is a combination of two different drugs: Diphenoxylate and Atropine. Diphenoxylate works by disrupting the flow of the intestinal bowels, thus preventing and eliminating frequent bowel movements. However, since Diphenoxylate has narcotic properties, taking it in large doses can lead to a sense of euphoria. This can cause the drug to be misused and abused, or sold as an illicit street dug. In order to prevent this…