winter Olympic Games, Russian athletes were caught abusing HIF activators.22Normally, the HIF pathway is activated upon hypoxic conditions. Thus, the end result would be to stimulate EPO synthesis in order to restore the normal oxygen levels in the blood and to enhance angiogenesis. Giving exogenous HIF activators can imitate hypoxic conditions which leads to the…
Primary Angioplasty – A Life-saving Procedure Primary angioplasty is a term used to describe an angioplasty done as a life-saving emergency procedure in a patient with an on-going heart attack [PAMI - Primary Angioplasty in acute Myocardial Infarction]. The international accepted door to balloon time intervention is within 90 minutes and 3 to 6 hours from the onset of heart attack for PAMI. Doing angioplasty in a critical patient of heart attack is in itself challenging and doing so in the…
as the inflammatory responses proceed, epithelium forms under the scab as well. Eventually the wounds edges meet again and the scab is shed. Under the surface, macrophages remove neutrophils and the remaining clot. Then, capillaries grow from the blood vessels around the wound and vascularize that area. All of this is part of fibrosis, in which the clot is…
post workouts, as well as rehabilitation, the sequential compression pump effectively increases circulation to reduce swelling and leg pain, venous edema, lymphedema, post-thrombotic syndrome, peripheral arterial disease, diabetes and other conditions.Gentle air compression therapy improves blood circulation and enhances the pressure of muscular tissues to relieve sore muscles. EASY TO SETUP AND USE: Lightweight and portable, the leg compression pump is easy to use. Color-coded air hoses…
A US subsidiary of Dr Reddy's laboratory, Promius Pharma, has obtained the US FDA approval for a prescription spray for psoriasis. The spray named Sernivo is an external application and contains 0.05% betamethasone dipropionate. It can be used by patients over 18 years of age. Psoriasis is an autoimmune disease and a complex inflammatory skin disorder in which skin cells begin to multiply rapidly and form lesions that are red, itchy and patchy. The skin may become dry or cracked and may bleed.…
Chondroblastoma was first described in detail by codman in 1931 and so is occasionally referred to as codman’s tumo r. Chondroblastoma was first described as calcified giant cell tumor by Ewing.11 Chondroblastoma constitutes a very rare bone tumor entity.2,6 In most cases it manifests between 10 to 20 years. Chondroblastoma are typically centered in an epiphysis. Although they occur most often in the end of a major tubular bone, they can appear in any secondary center of ossification, such…
laminitis. The hoof wall is made up of an interlinked outer insensitive layer (horn) supported by an underlying inner sensitive layer (laminae). In laminitis, the blood flow to the laminae is affected, resulting in inflammation and swelling in the tissues within the hoof, and severe pain. As the laminae are starved of oxygen and nutrient rich blood, the cells become damaged. Unless the…
patients who experience failure and require dialysis support .This nomenclature explains that renal failure occur as a continuum 1. AKIN recently defined AKI as “ functional or structural abnormalities or markers of kidney damage including abnormality in blood, urine or tissue tests or imaging studies present for < 3 months.”2 A large trial by Uchino et al.3, on the epidemiology and outcome of AKI in critically ill adult patients reported an overall mortality…
Sildenafil is a very important chemical, which was first described in order to treat the condition of pulmonary arterial hypertension. It was able to relax the arteries and help them carry more blood. The same function was found to be of great help to patients suffering from erectile dysfunction. Here, we describe the various benefits of the modern sildenafil pills and then discuss their side effects in order to avoid them in an ideal manner. Benefits of Sildenafil Sildenafil tablets offer a…
to help patients live longer until they get a heart transplant. Benefits of artificial hearts are that it is promptly accessible and there is no requirement for immunosuppressive medications. The diminished blood stream weakens the capacity of fundamental organs. Artificial heart raises the blood pressure and helps recovering vital organs while the patient is waiting for a heart transplant (HealthGuideInfo). This device has permitted patients to go home, even with a completely embedded…