Apoptosis

Typical clinical signs of V. vulnificus infections include fever, chills, diarrhea, nausea, vomiting, septic shock, and characteristic skin lesions [15]. These characteristic skin lesions include lower extremity cellulitis with ecchymosis and bullae. Since the organism can cross the intestinal mucosa rapidly, development of bullous skin lesions of the lower extremities can occur within the first 24 hours after onset of illness [16]. This onset if often thought of as an early manifestation of…

there would be small noncancerous polyps that are growths on the lining of the large intestine. When the cancer goes undetected for a long period it will proliferate and be noticed. When left untreated the cell proliferates and becomes resistant to apoptosis and leaves no room for normal cells causing carcinogenesis. There are cancer diagnostics and treatment methods to help lower the risks of cancer. Still cancer is the leading cause of death.…

Cancer Society, 2016). Oncogenes are gene that cause out of control cell growth that become cancerous. Tumor suppressor genes, are genes that slow down the cellular division that leads to errors in DNA repair, which prevents the cells from inducing apoptosis (You & Jones, 2012). Yearly, cancer causes 8.1 million deaths worldwide, and 14 million new cases arise. Currently, there are treatments…

1.7 III (b) VEGF: VEGF is also known as vascular permeability factor (VPF) is an endothelial cell specific mitogen in in vitro and is the main factor responsible for vasculogenesis and angiogenesis in a variety of in vivo models. The gene transcripts level of VEGF is stimulated at the time of implantation because process of implantation occurs under hypoxic condition. In rodents, VEGF is involved during embryo–endometrium crosstalk by regulating endothelial cell proliferation and vascular…

The most common immunologic responses of this pro-inflammatory multifunctional cytokines includes but is not limited to activation of signaling pathways for cell survival, apoptosis, inflammatory responses, and cellular differentiation (9-11). Primarily TNF are produced by type II transmembrane proteins, which are subdivided in to two groups based on their structure (14).TNF present in long amino-acid form produced by type II…

into the cancer cell and thereby induction of cancer cell apoptosis in a caspase independent mechanism. Earlier studies have been shown that breast cancer cells (BCCs) in a culture can phagocyte latex beads and fluorescent Matrigel. That study has confirmed the phagocytic activity by BCCs when using yeast as a test organism (40). The results of this study were demonstrated that phagocytosis of heat-killed Baker 's yeast induces apoptosis in the highly metastatic cells (MCF-7 and ZR-75-1) and in…

Abstract: The controversy in medicinal marijuana is investigated. The research question that drives this paper is the effects of medicinal marijuana on patients, where personal view or opinion do not take part in. Both sides of the controversy were considered with most discussed topics supported by two scientific experiments for each claim. Two experiments that strengthened the claim were: an experiment on a specific tumor cell (glioma) incubated with cannabinoids, and another experiment where…

2. Methods 2.1. Animals and procedures: 4-5 weeks old male Kunming mice weighing 19-21g were provided by Experimental Animal Centre of Kunming prior to treatment with LOS(10,20mg) or MET(20,40mg), the mice were either treated with vehicle (n=16) or ISO (n=80) for 2 weeks. The mice were fed food and had free access to tap water. The mice were maintained under stable room temperature and a regular 12h dark and light rhythm. Usage of experimental animal was in accordance with the compliance of the…

ATF3 function in cancer cells: oncogene vs. tumor suppressor The mouse homolog of ATF3 (named TI-241) was identified by differential hybridization due to its high expression in the extremely metastatic melanoma cell line B16-F10, and absence in the related but non-metastatic cell line B16-F1. While characterizing the ATF3 mouse homolog, it was found that over-expression of ATF3 in the non-metastatic B16-F1cells converted them into highly metastatic cells, therefore, suggesting that ATF3…

According to Ph.D. holder Pramod Dash, “it has been estimated that nearly 2 million people suffer some degree of head injury every year in the United States alone.” The Centers for Disease Control and Prevention estimates that about 1.7 million people in the United States have a traumatic brain injury each year. Brain injury can be defined as something that isn’t hereditary, degenerative, or present at birth that causes damage to the brain. The most common types of brain injury are traumatic…