Apoptosis

“Cancer”, its a disease that has claimed the lives of millions, its a disease that so far has no known cure, and its a disease that has many different forms. Cancer is defined as a malignant growth or tumor resulting from the division of abnormal cells. Heart cancer is one of the many different forms of cancer that affects us and luckily is one of the rarest cancers that we don’t see everyday. For example, one study reviewed more than twelve thousands of autopsies and found only seven cases of a…

mutation increase the chance of misfolding in proteins which is the case in the genetic or familial case of NDs [22]. Though the mechanism is not clear, it has been proven that deposits of misfolded proteins are known to be neurotoxic and able to cause apoptosis in neuronal cells. There are however mechanisms that are able to inhibit aggregation of proteins and protect the CNS from such danger. Examples of these include the chaperones that are able to bind to misfolded protein and cause them to…

begins to kill. Some gene therapies are specified to block the processes that cancer cells use to exist. An example is that cells in the body are expected to die when their DNA is unable to be repaired which happens after a certain amount of time (apoptosis). Cancer cells block this natural process, which allows for the tumor of malfunctioning cells. Some gene therapy strategies aim to reverse this blockage, which leaves the cancer cells with no other option but to die. Gene therapy, as…

Using infliximab to treat Crohn’s disease Introduction Crohn’s disease is a type of IBD that causes inflammation in any part gastrointestinal tract from the mouth to the anus. In response to this inflammation, the body’s immune system attacks the GI tract (Dessein, 2008). The progression of this chronic inflammatory disease is brought about by the action of several cellular processes and pro-inflammatory mediators (Poggioli, 2007). Because there is no single factor that can be targeted to…

The effect of opium on diethylnitrosamine-induced gastrointestinal cancer in rats Uncontrolled growth of abnormal cells and their spreading to another tissues ,these characterizing of cancers which mostly lead to death ,if their spreading is not controlled.Cancers are caused by chemical materials ,infectious organisms,tobacco and radiation as external factors and hormones,mutation and immune conditions as internal factors.(1) Gastrointestinal cancers are the term for many cancers which…

Multiple myeloma is a form of cancer that is caused by the formation of abnormal plasma cells, which become malignant. Plasma cells arise from B lymphocytes that are formed in the bone marrow; specifically the lymph nodes and spleen. When a foreign particle enters the body the immune system triggers an immune response which triggers B cells to produce plasma cells. The plasma cells make immunoglobulins. Immunoglobulins are antibodies that attaches themself to the target antigen in order for…

breast cancer. BRMS1 blocks spread of breast cancer by binding with histone deacetylase complexes (HDAC) and aberrant gene regulation is the outcome of this interaction. NF-kB (nuclear factor kappa B), activated in many malignancies and important in apoptosis, is negatively regulated by BRMS1. Two hyper methylated CpG islands are found in BRMS1…

Brain injuries in neonates cause marked chronic disability and can have a profound impact on the quality of life both in the patient and for their family. Causes of Neonatal brain injuries include stroke, hypoxia - ischaemia, foetal inflammation, reperfusion injuries, metabolic pathway insufficiency, and birth asphyxiation events. It is important to note that the type of injury seen in the neonate is largely dependent on age at the time of insult. In premature…

A form of ‘cultural apoptosis’: the ‘cells’, or individuals, subject to the culture of the body, self-destruct when stimuli or a suppressing agent is introduced in the systemic removal of damaged, disrupted, or unwanted cells. The synthesis of humanity predicates a break in the…

Introduction All animals can heal their wounds. However, some animals can even regenerate lost body parts. Questions have arisen such as, how does this process take place? What is necessary for these animals to perform this job? Experiments have shown that different animals regenerate in different ways. Some may be similar than others and it may have an impact on their lives. The purpose of regenerating tissues is to limit damage and loss of infection. The processes of tissue regeneration…