Introduction The immune system is a collection of cells, tissues and molecules that protect our body from toxins and microbes in the environment. It serves as our defense against molecules that our body does not recognize as its own. This system contains two divisions: the innate immune system and adaptive immune system. Both systems differ in the types of cells produced and the time and length in mounting a response. Inflammatory bowel disease is a chronic inflammatory disease including…
Cells can become cancerous when gene regulation is disrupted. Factors affecting gene regulation include mutations in DNA sequence, nucleosome positioning, chromatin organization and epigenetic changes in DNA methylation and histone modifications. Numerous genetic mutations of inherited cancers have been identified, as there is a large body of research dedicated to identifying DNA mutations that are linked to tumor initiation. After initiation, tumor progression often occurs due to multiple…
per day. For example, the last group, birth to age 2, was given a whole-cell pertussis containing vaccine, a typhoid vaccine and other vaccines in a single day resultant in the single-day exposure to antigens. There was not a significant increase to the risk of ASD with the exposure to more antigens. There was also little change when thimerosal was added. Discussion: From all case studies and control groups there is no link with vaccines being the cause of autism. The concerns that parents…
More to blood than meets the eye All blood may look alike, but beyond the elements that make up blood there’s a distinction that makes up four principal blood types: A, B, AB, and O. Blood type is determined by what kind of antigens the red blood cells have on the surface. Antigens are substances that help the body differentiate between its own cells…
There are many challenges to successful organ transplants, including matching a recipient and a donor based on matching genetic variability. It is extremely difficult to match MHC perfectly with a donor and a recipient as there are many locations where genetic differences can still cause a rejection reaction by the recipient. A familial donor is usually the closest to a perfect genetic MHC match that a recipient can find. The closer the match of genetic variability, the better the chances that…
reacting alloantibody. 2.Since the auto control didn’t agglutinate, an alloantibody is suspected. With that being said, it needs to be one that reacts at room temperature. Furthermore, based on the antigen typing of the patient P1 is suspected to be interfering with the ABO results. The Lewis antigen was ruled out due to it being present on the patient’s RBCs. Moreover, from the panel results (Jsa), Fya, (S) are also unexpected antibodies that need to be considered when transfusing the…
organisms invade the body. They recognize certain antigens based on their epitope, which is usually five to eight amino acids long on the surface of the protein. Western blot is used to visualize the proteins that will respond to specific antiserum after we separate the proteins. Then place the serums against nitrocellulose…
Blood is everywhere, in everyone, in all living animals. The type of blood and what makes it look how it does is all based on its composition. The uses of it are vital to all animals survival as it is the key component to living. Unknown to most, but the blood's composition must be kept at near perfect balance at all time for it to perform all its functions. Blood is a crucial part of an animal's existence. Without it, it could not survive. Blood has numerous types as well as appearances, and…
Immunity! To start with a personal experience, I have a brother who is almost two years old, Cullen. My family put Cullen in a school that also was a day care for babies. Cullen being around lots of sick babies ultimately got sick too all the time. Thinking about it having him exposed to those germs and bacteria will in the end build a strong immune system for him. So, immunity refers to resistance to disease. The innate defense system and the adaptive defense system. The innate defense system…
Not every patient that suffers from a heart failure is a candidate for a heart transplant. Some patients are sometimes too sick or have other medical issues that will not allow their transplant to be successful. In order to determine whether the patient is a candidate for a heart transplant, their medical condition must meet the requirements of the transplant team. Other tests may also be performed such as: echocardiogram, coronary angiogram or peak VO2 assessment. Echocardiogram measures the…