Measurement of glutathione Glutathione (GSH) is a ubiquitous tripeptide which serves several vital functions including detoxifying electrophiles, scavenging free radicals and providing a reservoir for cysteine. The sulfhydryl group of GSH reduces 5-5'-dithiobis (2-nitrobenzoic acid) (DTNB) and form the yellow colour product 5-thio-2-nitrobenzoic acid (TNB)21. Measurement of the absorbance of TNB at 412 nm provides an accurate estimation of GSH in the sample. Figure 7. Materials 5×105 cells/mL…
Patient Afib is a 58 year old, Caucasian, married male. The patient has been healthy most of his life with no significant health issues until the beginning of this year. One night, in April of 2016, patient Afib began to experience chest pain, shortness of breath, nausea, and vomiting prompting him to visit the emergency room. Subsequent tests revealed that patient Afib had symptomatic atrial fibrillation. Physicians in the ER stated that patient Afib probably had had atrial fibrillation for a…
Blood Transfusions – Principles Questions 1. Different components of WBC’s? How much of blood is plasma? 2. Function of RBC antigens? 3. Which blood type is universal recipient? Universal donor 4. Important facts about Rh factors? 5. Most fatal hemolytic reactions result from? 6. What are the procedures for donor/recipient blood? 7. How long does a type and screen take? What does it determine? 8. Type and crossmatch take how long? What three phases are performed? 9. Type A…
OUTLINE INTRODUCTION ATTENTION GETTER: Have you ever felt intense pain at your joints like you are unable to move your joints because of the severe pain that you felt. That pain is extremely painful especially at the big toe followed by whether your knee, ankle, wrist, finger and elbow. The pain may subside in hours to days but you don’t even know what’s the problem. You might start to notice the warmth and swelling at your joint,…
World War I introduced to the world many new articles to the field of technology. Although technology today is more advanced than in WWI, technology thrived during WWI to meet the ever changing needs of the crisis, accordingly, WWI had a big impact on the technology in the present. World War I pushed for headways in the realm of medicinal services, made new strategies for offense and guard, and finally, affected the innovation of the present day. The introduction of prosthetics helped give…
prostaglandin responsible for regulating the acid production in the stomach and the mucous lining that prevents the acid from corroding the stomach walls. Expectedly, some people suffer from stomach upsets and ulcers after taking aspirin. The anticoagulant effect of aspirin from blocking COX 1, while it is important in reducing the risk of recurring strokes, is problematic when it comes to closing wounds. Even so, selective COX 2 inhibitors work well to bypass these…
This paper explores many pieces of literature which describe the world of dementia. The articles go into length on the severity of the specific types of dementia, provide well built explanations of the types of dementia, symptoms, and provide various symptoms and common treatments. This paper will include a case study which dives into a patient's history, state their symptoms, and conclude with a final diagnosis. As there are many ways to treat a patient, research on medications and therapies…
An invasive approach including percutaneous coronary intervention (PCI) improves clinical outcomes in clients with ST-segment elevation myocardial infarction (STEMI) and in clients with non-ST-segment elevation acute coronary syndromes (NSTEACS) (Mehta et al., 2012). Periprocedural major bleeding is a strong autonomous predictor of early and late major adverse cardiovascular events and mortality (Bertrand, Larose, & Rodes-Labau, 2009; Verneugt, Steinhubl, & Hamon, 2011; as cited in Bernat et al.…
The patient for this case study is a Caucasian male in his late fifties who is retired. The patient arrives at Roper Rehabilitation Hospital via EMS from home. Patient’s wife reports a friend reported to her an abnormal gait pattern the day prior. Patient’s wife reports slurring of speech today. Patient’s CT scan results indicated Cerebrovascular Accident (CVA)/Hemorrhagic Stroke /saccular aneurysm in the cerebellar brain site. According to O’Sullivan (2007), a stroke (CVA) is an acute onset of…
Pulmonary Embolism: “The Silent Killer” “Help! Help! Help! Why do I feel as if I’m going to pass out? What is this stabbing feeling in my chest? I need to go to the emergency room right now!” Those are just a few of the thoughts racing through my head on November 3, 2015 the day I will never forget. The day the doctor told me, “You have a mass covering your left lung and it looks as if it may be cancerous, so a biopsy is necessary.” He went on to tell me in a flat tone that they needed to…