mutations in the TSHR gene, which encodes the TSH receptor protein. Graves' disease, an autoimmune disorder is the main cause of hyperthyroidism producing antibodies by the immune system arouse the thyroid to produce too much T4. Hyperthyroidism can be caused due to many conditions likes grave’s disease an autoimmune disorder, producing antibodies to excite thyroid gland to produce excess hormone, and causing inflammation of thyroid Gland. Drug induced, excess intake of iodine…
trials. In order to detect any changes in Bcl-2 and survivin levels due to treatment, western blotting was conducted using cells from each dichloroacetate concentration after 48 hours of treatment. Blots were stained with Ponceau S before probing with antibody to control for protein loading. To detect mitochondrial activity, hydrogen peroxide concentrations were to be measured using an Amplex Red kit. Each treatment would be measured after 24 and 48…
called R-EPOCH. Rituximab is a chimeric monoclonal antibody against the protein CD20 which is mostly found on the surface of immune system B cells. (Rituximab, 2015) Prognosis of Burkitt lymphoma (BL) in children, depends on the bulk of the disease at the time of diagnosis, Intensive systematic chemotherapy is the ideal choice of treatment for BL, which means the boy will be staying at hospital for a few weeks, he can also be given a monoclonal antibody drug called rituximab alongside the…
factor-a (TNF-a). The cytokine TNF-a is a proinflammatory, recognized to encourage HIV-1 reproduction and is involved in the development of HIV-1 related infections. This study done on the blockage of the cytokine TNF-a by chimeric humanized monoclonal antibodies (CHMA). CHMA are created by the combination of heritable substance obtained from a non-Homo sapien origin (Rabbit or Rat) with genetic material from a human being. Using the CHMA -- anti-Carbonic Anhydrase II (cA2), as the inhibitor of…
disease is an autoimmune disease that affects the Thyroid. “With Hashimoto’s disease, the immune system makes antibodies that damage thyroid cells and interfere with [their ability to make production of hormones produced in thyroid gland which include triiodothyronine (T3) and thyroxine (T4)]” (Cooper, 2012). When a person has Hashimoto thyroid disease “the immune system produces antibodies that attack the thyroid” (Cooper, 2012). This can cause a persisting impairment of the thyroid causing it…
physically superior for a mom and her young. Breast milk contains many growth factors and antibodies which stimulate the growth of the child and protect the child from illnesses for example, diarrhea, ear infections, many different types of rashes, allergies, asthma, and even skin problems, pneumonia, respiratory illness, etc... which improves the baby's chances of remaining a health life, none of these antibodies are even found in formula, and cant even be sustained. Most of these ingredients…
stop bleeding. White blood cells that fight infection and disease. A lymphoid stem cell becomes a lymphoblast cell and then one of three types of flymphocytes or white blood cells: B lymphocytes that make antibodies to help fight infection, T lymphocytes that help B lymphocytes make the antibodies that help fight infection. Natural killer cells that attack cancer cells and viruses.In a child with ALL, too many stem cells become lymphoblasts, B lymphocytes, or T lymphocytes. These cells are…
A concussion, a type of traumatic brain injury, causes malfunctions in ones brain. The major causes of the malfunctions are due to the damage of neural functions. The damage of neural function can lead to vision disturbance, instability, and slow cognitive recognition. There are other symptoms that are associated with concussions that have not been listed. A person can be suffering from a concussion with out their knowledge. Concussions affects a person’s function rather than the structure of…
They had 129 suspected cases and 176 controls. Among the suspected cases, 54.4 % were diagnosed with CHIKV. Among the control group, 30.1% of the participants were found to be positive to serology for antibodies. Those who were positive to IgG were excluded as they were testing for IgM antibodies to CHIKV. Central/East African CHIKV genotype is a causative virus. The study showed that reducing exposure to the sick patient during the viraemic phases was among the ways to avoid further…
Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare, neuromuscular junction autoimmune disease. The immune system produces immunoglobulin G antibodies against voltage-gated calcium channels (VGCC) residing on the cell membrane of the presynaptic nerve ending.1,3,5,6 The etiology of LEMS is decreased exocytosis of the neurotransmitter acetylcholine from presynaptic neurons into the neuromuscular junction (NMJ) caused by autoantibodies attacking VGCCs.3,7.10 There are two distinct groups of LEMS…