In Lisel Mueller’s poem “Reading the Brothers Grimm to Jenny,” the narrator details the relationship that he or she has with Jenny. Jenny is a character who is facing her own internal conflicts, but displays innocence and truthfulness to the narrator. As a result of this display, the narrator is conflicted about telling fairytales to Jenny. Moreover, the narrator is concerned with the high qualities and ideas that she attributes to people who are not worthy, who the narrator deems unworthy. To…
Dexter Morgan, age 42, blood splatter analyst for the L.A.P.D., hardworking, focused, and determined, a serial killer of serial killers. Wait, what? That’s right, a man seemingly just like you and me harbors a substantially large secret. But don’t all of us harbor secrets as well? Secrets that we don’t want anyone else to find out? Is this why we’re so drawn to people like Dexter Morgan, the anti-hero? The answer is yes because secretly they are representations of our own unconscious. Whether we…
Introduction: The main purpose of this experiment was to take the Gas Chromatography/ Mass Spectrum part of the “Analysis of US bills for cocaine using gas chromatography / mass spectrometry” lab and improve upon the gas chromatographic results. This would be done by finding a way to separate the peaks of cocaine and doxepin. The lab done previously showed the use of two different methods to obtain samples of cocaine and doxepin for spiked dollar bills. The two extraction methods were…
Observe Ligand-Protein Interaction using Gel Filtration Chromatography (Phenol Red Binding to Bovine Serum Albumin) Introduction: Serum albumin is often known as blood albumin, and is the most abundant protein in humans and other animal plasma. Serum albumin is also known as a carrier protein by non-specifically binding several biomolecules. It is essential for maintaining the osmotic pressure that is needed for body fluids distribution between body tissues and intravascular compartments.…
Raju Chandra et al; A reliable and reproducible reversed-phase high performance liquid chromatography (RP-HPLC) was developed for the quantitative determination of quetiapine fumarate from marketed bulk tablets. The active ingredient of quetiapine fumarate separation achieved with C18 column using the methanol water mobile phase in the ratio of 30:70 (v/v). The active ingredient of the drug content quantify with UV detector at 359 nm. The retention time of quetiapine fumarate is 5.27 min. A good…
Adsorption is the bond of particles, particles, or atoms from a gas, fluid, broken down and attached strongly to a surface. This procedure makes a film of the adsorbate on the surface of the adsorbent. This methodology varies from absorbtion, in which a liquid (the absorbate) pervades or is absorbed by a porous solid. Adsorption is a surface-based procedure while absorption includes the entire volume of the material. The term sorption envelops both methodologies, while desorption is the converse…
3.7 ANALYTICAL METHOD FOR ESTIMATION OF RALOXIFENE HYDROCHLORIDE IN HIGH PERFORMANCE LIQUID CHROMATOGRAPHY USING ACETONITRILE:0.05M AMMONIUM ACETATE (33:67) AS MOBILE PHASE 3.7.1 For Plain Drug Estimation Mode Reverse Phase HPLC Column C18 Detector UV Spectrophotometer Mobile Phase 0.05M Ammonium Acetate (pH 4): Acetonitrile Sample Raloxifene Hydrochloride in Methanol HPLC Flow Rate 1 mL/min Injection Volume 20µL Retention Time 4.6 min Λmax 289nm A stock solution of Raloxifene Hydrochloride was…
Light spectroscopy has become an incredibly useful tool in analyzing the structure and composition of compounds. Specifically, the principles of absorption, the process by which an electron absorbs radiation to excite from a lower energy state to a higher energy state, and fluorescence, the emission of photons when a material is subjected to radiation, allow for the identification and analysis of unknown concentrations of compounds.1 With that being said, the purpose of this experiment is to…
The aim of this experiment was to investigate which technique – out of gravimetric analysis and colourimetry – was the most appropriate and accurate method to practice when calculating the percentage yield of a reaction. When examining the data obtained from the investigation, there was evident that there were some trends in the results. For the three graphs showcasing the results for gravimetric analysis in task one and task two, there was no general pattern. This was due to the fact that in…
MDMA (3,4-methylenedioxymethamphetamine), commonly referred to as ecstasy, and methamphetamine are central nervous system stimulants, which can produce euphoria, enhanced mental and emotional clarity, sensations of lightness and floating, and other hallucinations. (Chandra et al. 2015) Due to their effects, MDMA and methamphetamine are used in Drug-Facilitated Crimes (DFC), intended to impair behaviour, perceptions, or decision-making capacity to take advantage of an impaired person without…