Analytical engine

Light spectroscopy has become an incredibly useful tool in analyzing the structure and composition of compounds. Specifically, the principles of absorption, the process by which an electron absorbs radiation to excite from a lower energy state to a higher energy state, and fluorescence, the emission of photons when a material is subjected to radiation, allow for the identification and analysis of unknown concentrations of compounds.1 With that being said, the purpose of this experiment is to…

The aim of this experiment was to investigate which technique – out of gravimetric analysis and colourimetry – was the most appropriate and accurate method to practice when calculating the percentage yield of a reaction. When examining the data obtained from the investigation, there was evident that there were some trends in the results. For the three graphs showcasing the results for gravimetric analysis in task one and task two, there was no general pattern. This was due to the fact that in…

MDMA (3,4-methylenedioxymethamphetamine), commonly referred to as ecstasy, and methamphetamine are central nervous system stimulants, which can produce euphoria, enhanced mental and emotional clarity, sensations of lightness and floating, and other hallucinations. (Chandra et al. 2015) Due to their effects, MDMA and methamphetamine are used in Drug-Facilitated Crimes (DFC), intended to impair behaviour, perceptions, or decision-making capacity to take advantage of an impaired person without…

Introduction: This Laboratory experiment mainly focused on the fundamental concepts of basic Chromatography. We had a goal of learning about the properties of color additives, studying their molecular structures, and their rates of solubility when added to a strip of paper and temporarily placed into a beaker of solution. When actually performing the experiment, it is relatively easy and straightforward to do as long as you do not increase the concentration of the dye or leave the wrong side of…

3. Results and discussion 3.1 Microstructural characterization The Roman spectrum of Cr-DLC coating was shown in Fig.1. The overlapped D peak and G peaks located at 1363cm-1 and 1564cm-1 were obtained after fitted with Gaussian curves, respectively. It’s well known that the content of the graphite crystal was closely related to the value of ID/IG [22]. And the ratio of intensity between D peak and G peak (ID/IG) of Cr-DLC coating could be calculated by the fitted curve. The value of ID/IG was…

3.3.9. Encapsulation efficiency of drug loaded NPs The encapsulation efficiency (EE) was determined by weighing the amount of unloaded drug recovered from lyophilization of the supernatant obtained after centrifugation of NPs. The drug encapsulation efficiency was calculated according to the following equation: Encapsulation efficiency (%) = (Winitial/Wfree)/Winitial *100%. Where, Winitial and Wfree are the weight of initial drug and the weight of free drug determined in the supernatant after…

Male or female Sprague-Dawley rats (8–12 weeks old) were purchased from Damul Sciences (Daejeon-si, Korea). This study was conducted in accordance with the Guidelines for the Care and Use of Laboratory Animals and approved by the Institutional Animal Care and Use Committee (IACUC, No: IACUC140047). Over the acclimatization period and during the study, the range of temperatures and humidity were recorded daily; ambient temperature was maintained in the 25 ± 1 °C range; humidity level was measured…

Carl Jung was a swiss psychiatrist who believed that the human psyche consisted of three parts: the ego, the personal unconscious and the collective unconscious. According to Jung, archetypes are universal patterns which exist in the collective unconscious. He believed these recurrent images possessed universal meanings that appear in literature. Carl Jung theorized that archetypes lead to insight on humans and the world around us. Jungian archetypes can be identified in nearly all literature,…

“DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF CEFTRIAXONE AND TAZOBACTAM INJECTION USING RP-UPLC METHOD” 2.1 OBJECTIVE To develop and Validate Stability Indicating Method for simultaneous estimation of Ceftriaxone and Tazobactam in their combined dosage form by RP-UPLC method in various stress condition like, alkaline, acidic, oxidative, thermal and photo degradation. 2.4 METHODOLOGY 2.4.1 Chromatographic Condition Column Separation was achieved by…

RESULT AND DISCUSSION 7.1. Preformulation studies 7.1.1. Identification of pure drug by FTIR Figure7.1: Identification of Sample through FTIR Figure 7.2: FTIR Spectrum of Standard Prazosin hydrochloride (with references of B.P.- 2009) Table: 7.1 - Characteristics peaks of Prazosin hydrochloride S.No. Reference peaks (cm-1) Theoretical peak of Prazosin hydrochloride Obtained peaks (cm-1) Functional Group Stretching/ Bending 1 1750-1680 1529.92 1529.92 C=O Stretching 2. 1650-1580…