Amyloid

of two different types of proteins which are called Beta-Amyloid protein and Tau Protein. These proteins are usually formed to help our brain cells’ communication. Like for example Beta-Amyloid protein is a protein that is usually released from a bigger protein called the APP protein (In which the APP protein is located on the surface of the cell) that usually used to be cleared inside the body. But in Alzheimer’s disease the Beta-Amyloid…

Alzheimer's disease is the most common type of dementia that affects the central nervous system by causing cognitive problems. Alzheimer’s is a progressive disease, meaning that this disease gets more severe over time. It is estimated that 700,000 people in this country will die from Alzheimer’s this year, making it one of the highest causes of death in America. As of right now, there is no cure; however treatments are available to help reduce the symptoms of this disease. Alzheimer's is most…

Have your ever missed placed your car keys and went crazy looking for them? This is how people with Alzheimer feel every day. Alzheimer’s disease is a form of dementia that causes memory lost, confusion and difficulty understanding questions (Mnt, Oct). This disease has been around for more than a hundred years and received its name from Dr. Alois Alzheimer. In 1906 Dr. Alzheimer performed a cerebral autopsy on one of his patients that was experiencing memory lost and confusion prior her death.…

Although Mrs. Moor was able to talk about the past events, she could vaguely recall and describe the details of her stories. In addition, she could not remember her birthday, her age, and her medical conditions. She hadn’t lost touch with the presence yet; she seemed to be unaware about the fact that she repeated her stories multiple times during the interview. Thus, we suspected that Mrs. Moore might be in the early stage of Alzheimer’s disease. The term dementia is commonly used to describe a…

(Mendiola-Precoma et al., 3-6). Specific genes are theorized to be significant indicators of Alzheimer’s. Experts Mendiola-Precoma et al. claim that certain gene mutations could predispose one to Alzheimer’s disease, specifically three being, “... (a) the amyloid precursor (APP) gene on chromosome 21, (b) presenilin 1 (PSEN-1) gene on chromosome 14, and (c) presenilin 2 (PSEN-2) gene on chromosome 1” (1). Genetic factors, as well as diseases, could be large contributors to predisposing one to…

severely affects protein activity and its main technique of cellular signalling and regulation. In the neuron, Pin1 encourages cellular health by restoring amyloid precursor protein and phosphorylated tau protein to functional state. In Alzheimer’s disease there is a loss of Pin1 gene and this loss of Pin1 gene leads to overproduction of β-amyloid and the accumulation of abnormal tau. In cancer, this Pin1 gene is overexpressed hence promoting oncogenesis through different signal pathways…

‘With an estimated 425,416 individuals living with it, Dementia is the second leading cause of death of Australians contributing to 5.4% of all deaths in males and 10.6% of all deaths in females each year.’ (Dementia Australia, 2018) Genetic testing is a fundamental phenomenon in 21st century society. Testing processes reveal the likelihood of an individual inheriting, passing on, or living with a suspected genetic condition. These medical tests identify any changes in proteins, chromosomes or…

Scientists are not positive of what causes cell death and tissue loss in the Alzheimer 's brain, but plaques and tangles seem to be the cause. Plaques are formed by protein pieces called beta-amyloid. Beta-amyloid comes from a larger protein found in the fatty membrane surrounding nerve cells. Beta-amyloid is chemically "sticky" and gradually builds up into plaques. The small clumps may block cell-to-cell signaling at synapses. They may also activate immune system cells that trigger inflammation…

The lay people associate Dementia with memory loss, but it’s just not that simple. Dementia is a gradual disease with many other characteristics, such as, loss of attention, orientation, language, judgement, and reasoning (Lewis, Dirksen, Heitkemper, Bucher, & Harding ). “Personality changes and behavioral problems such as agitation, delusions, and hallucinations may occur” (Lewis, Dirksen, Heitkemper, Bucher, & Harding). All of the issues that come with Dementia affect the entire person’s…

It starts with simple forgetfulness. “Where are my keys?” and “What day is it?” were questions that Betty began to ask when she reached her golden years. She was soon forgetting how to get to the grocery store and couldn’t remember the names of her children. Before long, she was diagnosed with Alzheimer’s Disease, and it was quickly advancing. For months, Betty’s family struggled with the tantrums she would throw when someone urged her to attempt to remember something. Betty knew she was…