Amine

Synthesis of Schiff base Method preparation for Schiff base ligand is a straight forward synthesis and easily modified using different amines and carbonyl compound. This could be one of the reasons that make Schiff base ligand popular in coordination chemistry research. Synthesis of Schiff base ligand commonly, taking place in alcohol through condensation reaction of amines and carbonyl compound. The acid/base catalysis or heating is employed in the synthesis of Schiff base as their reactions…

Introduction Determining the concentrations of proteins is necessary for a variety of different reasons. For example, protein concentration must be known in order for proteins to be used in enzyme reactions, as the correct stoichiometry must be known. Another example is protein purification; during protein purification the quantity of protein present must be known to determine the yield1. The quantification of proteins is determined by methods known as protein assays. There are different…

Case study 4 Even in the absence of a known drug target, a drug can be designed to perform a specific function through the testing of a variety of substituents. Through this, the biological activity of each substituent can be determined in order to create the final product in the form of a marketable drug. An example of this is oxamniquine, which is a drug that is active against schistosomes, the causative agent for schistosomiasis (Patrick, 2013, p. 305). Schistosomiasis, caused by three…

For years, Indiana has been plagued with problems related to methamphetamine and pseudoephedrine. Since the year 2013, Indiana has ranked highly in methamphetamine-related categories out of the fifty states. Pseudoephedrine is a sympathomimetic amine, which means that it has effects on the sympathetic nervous system. The synthesis of pseudoephedrine into methamphetamine is dangerous, has led to the question of needing a prescription for pseudoephedrine, and has brought forth ethical and legal…

The Endocrine System is considered to be an integrative system because the hormones which are produced by this system act at the distance, many of those substances act in the different organs. The endocrine system and nervous system work together to coordinate functions of all systems in human body, they are responsible for maintaining the internal environment, nearly all physiological processes are affected by the hormones. They regulate almost all body function starting from metabolism, grow…

Protein aggregation is the process whereby proteins are misfolded. It is a phenomena that has been widely discussed in the scientific community over the recent years as it can lead to detrimental effects on our health such as neurodegenerative diseases. In this essay, I will be discussing the structure of a protein, its role in the human body as well as protein aggregation and the negative consequences it has on our health. Proteins are large molecules, also known as polypeptide chains which are…

better and cheaper form has emerged for knee replacements. 3D knee replacements Many knee replacements are caused by osteoarthritis and researchers have found that a gene called FAAH is higher in people who have osteoarthritis. FAAH is fatty acid amine hydrolase, which is a membrane hydrolase with a single N-terminal transmembrane domain. In the past, the FAAH gene has been directly correlated with pain sensitivity. FAAH is also a gene known to balance and deactivates anandamide, meaning…

In the first step of the experiment, m-toluic acid reacted with thionyl chloride to form the acid chloride derivative of m-toluic acid. In this reaction, the carboxylic acid is first converted into an acyl chlorosulfite intermediate, replacing the –OH of the acid with a better leaving group. The acyl chlorosulfite then reacts with a nucleophilic chloride ion, at which point the chlorosulfite leaves in the form of sulfur dioxide and chloride ion. The remaining acid chloride then reacts with…

Hrothgar told Beowulf after the second battle, the one with Grendel’s mother “you have made yourself immortal by your glorious action”. According to Tolkien’s vision, humans create circles of light as is reflected in the poem by Hrothgar Mead Hall in which there is laughter, music, and fellowship. And outside those circles are all the forces that want to destroy it. The very fact of building the Mead Hall calls Grendel into existence. Therefore, we were backwards in the poem from a more nearly…

Data Calculated from Experiment Solid-Liquid Weight (g) Solid-Liquid % Recovery Liquid-Liquid Weight (g) Liquid-Liquid % Recovery Acid 0.01 20 % 0.028 56 % Phenol 0.011 22 % 0.001 2 % Amine 0.013 26 % 0.005 10 % Neutral 0.03 60 % 0.026 52 % Table 1 shows the data obtained from this experiment of both the solid-liquid extraction (on the left side of the table) and the liquid-liquid extraction method (on the right side of the table). It shows that in the solid-liquid extraction, most of the…