Amine

Methylphenidate, commonly known as Ritalin, is a commonly prescribed central nervous system stimulant used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Medical use of methylphenidate began in 1960 and an estimated 2.4 billion doses are prescribed a year. Methylphenidate is thought to act through the inhibition of dopamine and norepinephrine transporters in neurons, especially those of dopaminergic pathways of the brain. The dopaminergic pathways of the brain are…

just one way of delaying the process of the disease as well as improving the quality of life for the patient. Henceforth Amsacrine is one to watch out for due to its specific mode of action. Reference. Amsacrine has an acridine chromophore with an amine at the 9 position (fig 1.) used in the treatment of some types of lymphoma or acute adult leukaemia [5]. It can also be known as Amsidine or m-AMSA [1]. Lymphoma is a cancer of the lymphatic system and leukaemia, a cancer of the blood [2,3].…

Question 1. A. AIRWAY– Maintaining a clear airway is always considered a high priority because the airway is essential for gas exchange. However, the patient has a patent airway (Ramkumar, 2011). The nursing strategy is to conduct an airway assessment “look, listen and feel” continuously to detect any changes. This is to provide immediate respiratory care if the patient’s airway is compromised (Higginson, Jones & Davies, 2011). This is a low priority. B. BREATHING – Respiration is altered due…

neuroblastoma as glioma in 1891. In 1927 scientist Cushing and Wolbach labeled neuroblastoma as ganglioneuroma which are similar tumors compared to neuroblastoma. In 1957, Mason published a report of a child with neuroblastoma whose urine contained pressor amines. This discovery really contributed to the understanding of neuroblastoma. Throughout the history of neuroblastoma there weren't many patterns of the cancer appearing in a certain race or gender. Neuroblastoma is still a very rare cancer…

Chemistry: Enasidenib is a first in class, a selective allosteric inhibitor of mutant isocitrate dehydrogenase-2 (IDH2) inhibitor discovered at Agios Pharmaceutical, Inc. in the United States of America. Recently, on 1 August 2017, Celgene Corporation and Agios Pharmaceutical in cooperation won the approval for Enasidenib under brand name IdhifaTm for the treatment of relapsed/refractory acute myeloid leukemia. it is a white to off-white crystalline, non hygroscopic powder existing in…

The aim of the experiment was to investigate the initiation of the peristalsis reflex in a piece of guinea pig ileum through the stimulation of the stretch receptors, and subsequently demonstrate that the peristalsis reflex is neuronal in origin and not just a property of the muscle itself. Several drugs including lignocaine, atropine, hexamethonium, and nicardipine were induced to a piece of guinea pig ileum under a standard hydrostatic pressure of 5.0 cm/H2O, and hence the effects determined…

(Pental 2018, para. 2). The product manufacturer of bleach is Pental Products Pty Ltd located in Shepparton, Victoria (Pental Products Pty Ltd 2016). The chemicals contained in this product are sodium hypochlorite, sodium hydroxide and coco dimethyl amine oxide (Pental Products Pty Ltd 2016). Bleach has positive and hazardous effects on human health, in the context of household use as detailed in journal 1. In addition, the substance also has catastrophic consequences to larger environments;…

The major bottleneck for lipid extraction from the wet microalgae is the low extraction efficiency, because of the immiscibility of nonpolar organic solvents with water contained in wet microalgae {Yoo, 2012 #31} {Kim, 2013 #118}. Traditional method for lipid extraction from dry biomass uses a co-solvent system, which consist of a non-polar solvent and polar solvent {Halim, 2012 #7} {Kim, 2013 #118}. When the co-solvent system is directly applied to wet microalgal biomass, the microalgal cells…

REACTIONS OF ALDEHYDES AND KETONES ABSTRACT The difference between aldehydes and ketones is by having a hydrogen atom attached to the carbonyl group. This makes the aldehydes very easy to oxidize. Ketones do not have that hydrogen atom and are resistant to oxidation. They are only oxidized by powerful oxidizing agents which have the ability to break the carbon-carbon bonds. This report is about the reactions of aldehydes and ketones. This was done to determine how they react when different…

However, grilling can also present some types of health risks as two types of carcinogenic compounds which are produced: HCAs (heterocyclic amines) and PAHs (polycyclic aromatic hydrocarbons). These mostly are produced when the fatty meat is in directly in contact with the smoke or flame of the grill and can also be reduced by employing certain techniques whilst grilling. Try selecting leaner…