Muscular dystrophy is a group of noncommunicable diseases that is passed down through heredity lines. Noncommunicable diseases are diseases that developed in humans without other species interference and that cannot be passed between people. Muscular dystrophy can be broken up into nine major forms: Myotonic, Duchenne, Becker, Limb-girdle, Facioscapulohumeral, congenital, Oculopharyngeal, Distal, and Emery-Dreifuss. Muscular dystrophy can appear at any time in one’s life, typically in infancy or…
This research suggested that the system called the glympathic system which was named by (Nedergaard ,M.,& Goldman, S.A.(2016). They proved that beta-amyloid were disposed of during the sleep cycle at a much faster rate than when the body was active during the wake cycle. While the body is in the sleep cycle mode, the movement of fluids from cell to cell in the brain is being controlled and the process of disposing harmful proteins are properly channeling through the synapse however if the…
which results in disconnect throughout the body. MS is one condition that shows promise of the medical implication of cannabis to treat neurodegeneration, neuroinflammation, and overall protection of the central nervous system from demyelination of neurons (Baker, D., Jackson, S. J., & Pryce, G., 2007). As stated by Zajicek and Apostu, “Other prevalent symptoms include muscle stiffness and spasticity, poor mobility, pain, memory problems, tremor and balance trouble, urinary disturbance and…
Age-Related Macular Degeneration (AMD) is the most important cause of blindness in industrialized countries. The onset of macular neovascularization in AMD defines an advanced form of the disease characterized by exudative retinal changes due to an abnormal growth of newly formed vessels within the macula. This neovascularization has been divided into three types. Ref gass e ref freunf Type 1 and 2 neovascularization arise from the choroidal circulation and are refered to as choroidal…
Monosodium glutamate is a taste enhancing vegetable protein. At the time of discovery, MSG was thought to be safe since it was an amino acid, a natural substance. The amount of MSG added to foods has doubled in every decade since the 1940's and by 1972, 262,000 metric tons of MSG were produced. In 1957 two ophthalmologists, Lucas and Newhouse decided to test MSG on infant mice in an effort to study the effects of MSG and its correlation with an eye disease known as hereditary retinal dystrophy.…
Marfan Syndrome Near the end of the 19th century a french doctor Antoine Marfan was the first doctor to notice the effects of a common disorder (Atinder). Marfan syndrome is a genetically inherited disorder that affects the connective tissues that exist through the body. Specifically, Marfan syndrome alters the FBN1 gene and this affects the production of fibrillin (NHGRI). Fibrillin is a protein that is produced by the body to give strength to connective tissue. Without this protein,…
compartmentalization of signaling. It has been well established that neurons are highly polarized cells characterized by differential localization of proteins and mRNAs in different subcellular components. It is also shown that somatic and synaptic translation has a differential role in initiation and maintenance of…
In order to understand the hypothesis, first we must understand what is amyloid-beta, and how it is synthesized. Amyloid-beta is a peptide cleaved from the amyloid-beta precursor protein, which is a larger integral membrane protein found concentrated in neuronal synapsis (Masters et al., 1985;Glenner & Wong, 1984). An existing mutation in APP would lead to an increased cleavage and to a different availability of its sub products, hence increasing the amount of amyloid-beta being synthesized. A…
The Nervous System is divided into two major sections, the Central Nervous System (CNS) and the Peripheral System (PNS). The CNS contains everybody's brain and spinal cord; this is where our body receives sensory information, generates thoughts and emotions, and stores our memories at. Our PNS contains our nerves and axons; this section is responsible to give and take information to and from the CNS. Our Peripheral System is then broken into two more sections called the Somatic Nervous System…
“Parkinson’s disease is a progressive disorder of the nervous system that affects movement,” Mayo Clinic states. The most common or distinguished sign of the disorder is a tremor. The tremor usually begins in one of the limbs, most often the hand (Mayo Clinic). Another sign of Parkinson’s disease is a change in one’s speech. Someone with Parkinson’s might talk fast, quiet, with a slur, or there might be a slight delay before they begin to speak. Also, having stiff muscles is another sign of the…