Alpha 1-antitrypsin

by innate pattern recognition receptors (PRRs) impedes successful transplant tolerance. On the other hand, TLR signalling and Toll-like receptor-4 (TLR-4) polymorphisms were also found linked to allograft rejection and development of acute rejection.1 Moreover, immunosuppression on specialized cell-mediated immunity that equipped with TLRs and PRRs attenuate immune responses to toxins and infections. Patients suffer from rejection or infection often accompanied with clinical manifestation such…