Allele

These proteins aid in repairing damaged cells. When these genes are mutated, cell damage is not repaired properly. These mutated cells are likely to develop additional genetic changes that can then lead to cancer. Women who carry disease specific alleles for BRCA1 and BRCA2 are at higher risk of ovarian epithelial cancer than other women. Every person regardless of their gender has these specific genes. People have two sets of these genes from both their mother and father. These genes can be…

Practical 2 Title: Du Test by Tube Method Aim: To perform the Du test by tube method Introduction: The D antigen is the most immunogenic antigen in the Rhesus blood group system. Rhesus positivity and negativity indicate the presence or absence of the D antigen on the surface of red blood cell. Du test is the further testing that is done to identify Weak D antigen when the cells being tested have failed to react with anti-D antisera at immediate spin. An indirect antiglobulin test is…

Phenylketonuria A disease is an infection that happens because of outside bacteria or viruses. Meanwhile, a inherited genetic disorder is found in DNA and occurs when inherited by one’s parent. Numerous are caused by transformation in the quality of the cell. Having Phenylketonuria, your body won’t be able to process Phenylalanine, a protein that is in most of the foods. Phenylketonuria is usually found in people from Native American and Northern European ancestry and less common in people from…

The apterous gene mutations is a recessive trait that is inherited causing a varying phenotypes such as different wing deformities. Other phenotypes observed are the decrease in life span and female sterility. Ap is required to regulate gene expression needed for the development of Drosophila wings and haltere discs. Decreased ap activity due to the overexpression of dLMO results in wing mutations. The phenotypes displayed in apterous mutants are places them at a disadvantage compared to wild…

In the chapter titled, “Immortality,” Matt Ridley discusses the idea of the immortal cell theory. He presents some case studies as well as his own speculations. To began, he explains how the origin of the first cell is still alive in us today and although this is true it does not mean our species will live forever. The function of our life and all life is to reproduce but to get to that we have over came many challenges. On Chromosome 14, the presence of the TEP1 gene seems to be the source of…

We know that all living things need to make cells to survive. Old cells die and need to be replaced. In order for living things to continue to grow, cells are constantly being made. OpenStax states that the process of new cells being made is called cell division (2013). There are three types of cell division and those are binary fission, mitosis, and meiosis. Binary fission is a quick and simple process involving replication, elongation, separation, and daughter cells. Meiosis and mitosis are…

Objectives: To evaluate the association of glutathione S- transferase mu 1 (GST M1) and glutathione S- transferase theta 1 (GST T1) polymorphisms with the development of T1DM and disease-related risk factors. Materials and Methods: The study included 64 diabetic children with T1DM and 41 control subjects. They were subjected to: history taking anthropometric measurements and laboratory parameters included fasting glucose, serum creatinine, lipid profile, HbA1cand evaluation of GST T1 and M1…

Type 1 Diabetes Type 1 diabetes mellitus is an autoimmune condition that affects roughly 5-10% of all diabetics around the world. More commonly known as juvenile diabetes, and insulin-dependent diabetes, this disease can wreak havoc on a person’s immune system, and can lead to many life-changing events. Most type 1 diabetics are diagnosed under the age of 30, but it is becoming more common to find adults being diagnosed over the age of 30. Many attribute the development of type 1 diabetes to…

By Chelex based DNA isolation, DNA was isolated from buccal cells to study the genes TAS2R38, CDK3, ADH/ALDH, and D1S80. It was hypothesized that after gel electrophoresis, the TAS2R38 DNA sample will be cleaved at two places, since by the taste test was positive for PAV. The CDK3 gene will display one or two bands and the ADH/ALDH was expected to form one or three bands based on homozygosity or heterozygosity for the gene. D1S80 will have repeated sequences from 14 to 72 repeats. After…

Geneticists have worked towards sequencing the human genome since developing Sanger sequencing in the 1970s. The Human Genome Projected accomplished this in 2003, but now the public wants their own genome sequenced. Some companies have already started performing sequencing for profit. While clinical studies, perform and disclose results genetic sequencing to participants. However, there are scientific, and ethical issues surrounding personal DNA sequencing. Despite this, the advantages outweigh…