AKT

Abstract Angiogenesis is an essential process for organ growth and repair. Thus, an imbalance in this process can lead to several diseases including malignancy. Angiogenesis is a critical step in vascular remodeling, tissue damage and wound healing besides being required for invasive tumor growth and metastasis. Because angiogenesis sets an important point in the control of tumor progression, its inhibition is considered a valuable therapeutic approach for tumor treatment. Chronic liver disease…

Introduction: An important category of issues in medical science is the diagnosis of diseases, which is based on various tests on the patient. Cancer is the second most common non-accidental cause of mortality in the world. Today, cancer is one of the health problems of the world, and it costs a lot of research every year around the world, this is despite the fact that the third cause of death in our country is "cancer." Unfortunately, the wrong way of life has led to the emergence of cancers…

acquired most of the techniques you are currently using in the ongoing projects. My training in molecular biology research started during my bachelor studies in the group of Prof. Kavsan in Kyiv where I studied role of CHI3L2 protein in context of AKT pathways and glioma cancer. I received a broad training in main molecular biological methods and applied it to investigate the role of phosphorylation of our target protein in cell proliferation. I worked not only…

of the extra attention his sister Joy receives calling her - the bloody bay or something- quote. As Michael becomes more curious of Mina and Skellig, the symbolism of wings and birds becomes more frequent. Birds are often symbolised in the novel to akt as a translation between the metaphysical world and the physical world. After moving to his new home Michael did not look at birds or their wings until…

Coronary artery disease (CAD) is a narrowing of the small blood vessels that supply blood and oxygen to the heart. Coronary artery disease (CAD) is the leading cause of death worldwide. While the symptoms and signs of coronary artery disease are noted in the advanced state of disease, most individuals with coronary artery disease show no evidence of disease for decades as the disease progresses before the first onset of symptoms, often a "sudden" heart attack, finally arises (Gaziano et al.,…

How glucose levels are re-established when a disruption in the system by internal influences are made. An example of an internal influence that disrupts the negative feedback system of blood glucose regulation is diabetes. Diabetes is a disease in which the body is not able to absorb enough glucose into cells or does not get converted into glycogen, either because of the lack of insulin in the body or because the body does not respond to the insulin properly. Because the negative feedback…

Proteus syndrome is an exceptionally rare disorder that effects the growth of a wide spectrum of tissue types in the human body. Virtually any organ or structure of the body is vulnerable to its affects, which are most commonly characterized as being hamartomatous malformations. Due to its unpredictable nature, those of whom suffer from this condition experience distinctive mutations of their bodily tissues which appear asymmetrically and can be located randomly throughout the body. Although…

high level of blood glucose, and is transmitted from the outside to the inside of the cell. • PI3K passes the signal further, and attracts the protein AKT, which is phosphorylated by the proteins mTOR and PDK1. • GLUT-4 vesicle is held in a recycling state near the cell membrane until the protein that moves it becomes activated. • Fully activated AKT reaches GLUT-4 vesicles, which then activates the protein, which moves GLUT-4 vesicles to the cell membrane. • In the final step, many GLUT-4…

Peer Assessment 2 Choose one out of paracrine signalling, endocrine signalling, autocrine signalling and direct signalling and describe brie y the process by which this occurs. The Endocrine signalling occurs over long distances in the body and the signal is sent through the blood. Firstly, the cell inside the pituitary gland sends hormones into the blood stream over a long distance and once it gets reaches to a cell with the right receptor, the hormones will attach themselves to the receptor…

Article 4: Comparing the Teaching Interaction Procedure to Social Stories: A Replication Study The purpose of this study was to compare the effectiveness of teaching interaction procedure to social stories in a group setting by teaching children diagnosed with ASD social skills. The authors first discussed and explained that children with ASD have social skill deficits. They then presented research information on both teaching interactions and social story interventions. This study includes…