Analysis of Adenosine receptor blockage’s effects on the electrophysiology of HCTP/OR producing neurons of the Hypothalamus – receptor blockage mediated by Caffeine Introduction In this experiment, the quantification of firing rate changes on a specific neural sub-group will be analyzed via whole cell patch-clamping and the application of the common psychoactive drug-caffeine. The significance of quantifying the electrical signaling of the chosen neuron is to proportionally quantify the…
*Antibodies, antigens, agonists, target receptors, enzymes, inflammatory cascades, recombinant DNA. I now understood the cellular and molecular levels of my disease. My surgeons held out no hope of my responding to anything less than removal of my colon, terminal ileum and small…
circulation. It then enters the arterial circulation and moves quickly to the brain. Nicotine diffuses readily into brain tissue, where it binds to nicotinic acetylcholine receptors (nAChRs), which are ligand-gated ion channels. When a cholinergic agonist binds to the outside of the channel, the channel opens, allowing the entry of cations, including sodium and calcium. These cations further activate voltage-dependent calcium channels, allowing further calcium entry” (Benowitz, 2008). In the…
The antagonist and agonist muscles work in opposite directions of joint to help produce this movement and requires segmental and joint rotation in multiple planes. In order to generate linear at the foot, a skilled kicker will first rotate hip backwards into extension and flex…
Paul Pierre Broca talked about ‘le grand lobe limbique’ in 1878 or the great limbic lobe and used the term “limbic” (from the Latin limbus for border) to the rounded rim of the cortex which also has the cingulate and the parahippocampalgyri. However, its supposed role in emotion was elaborated by the American physician, James Papez in 1937 in the influential paper titled ‘A proposed mechanism of emotion’. This anatomical model is called the Papez circuit.[2] In the year of 1948 scientist…
Cannas et al. (2006) report on a 51-year old male PD patient, who began to show signs of PD at the age of 44. Two years later, the patient began to show a mild motor disability and was diagnosed with PD. He was then put on Peroglide, a dopamine agonist ergot derivative, which is commonly used to treat PD. At the time, he was not taking any other form of medication. After the introduction of this new medication, his wife reported an increase in libido, but there was no public activity. Three…
Alzheimer 's Disease Alzheimer’s disease is not a new disease. “Alzheimer’s” was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906. Alzheimer’s disease is an irreversible, progressive disorder involving neural degeneration in the cortex that slowly destroys the memory and thinking skills, and eventually the ability to carry out activities of daily living (Karch, 2013). In most people with Alzheimer’s, symptoms first appear in their mid-60, and accounts for…
PROTEOMICS AND NUTRIGENOMICS ASSIGNMENT: PUFA AS NUTRACEUTICAL SUBMITTED TO: DR. SANAULLAH IQBAL SUBMITTED BY: MAHAM ABID REGISTRATION NO. : 2014-ND-026 NUTRACEUTICAL Nutraceutical is referred to a functional food ingredient or a nutrient that possesses therapeutic properties and claim health benefits among people. CLASSIFICATION BASED ON CHEMICAL NATURE Nutraceuticals can be divided as follows: • Isoprenoid derivatives • Phenolic substances • Fatty acids and structural lipids •…
Hypertension Yocasta Mercedes Xiaopeng Zhou MD MED 115-M03 Summer 2015 Hypertension Is a cardiovascular disease, in which the blood pressure is abnormally high. For a person be Hypertensive the blood pressure has to be higher than 140 over 90 mmHg, this means the systolic reading is over 140 mmHg or the diastolic reading is over 90 mmHg. The blood pressure, in mmHg: Normal blood pressure is less than 120 systolic and when the diastolic is less than 80. Prehypertension is…
Pain can be an uncomfortable sensation that surges through our body that can range from mild to very painful. Although we don’t like to feel pain, it is a necessary occurrence in order to signal to the brain that we need to get away from the thing that is causing us the pain. In the previous paper, the journey from the nerves, to the spinal cord, and lastly to the brain was discussed. Information was sent through a multitude of action potentials from the afferent neuron to the 2nd-order neuron…