Agonist

Introduction: Pharmacogenomics is the study of how genes affect an individual’s response to drugs. This is a new field that combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop fruitful, safe medicines and doses that will be customized to a human genetic makeup. Now drugs that are available are “one size fits all,” but they do not effective for every person. It is very tough to augur that a person get benefit from drug or not, and…

present in the central nervous system, while recent evidence proposes that CB2 receptors are present on brainstem neurons. Both CB1 and CB2 receptors may have a role in mediating the cannabinoid effects on vomiting. Whether through a CB1 receptor agonist or with CB2 binding, cannabinoids directly and indirectly affect serotonin,…

What is meant by the placebo effect when it comes to pain medication is that the analgesic effects of “medications” that are in fact not medications at all but are still suggested to be possibly effective (the study states in double blind studies that the suggestion of a placebo effect doesn’t mitigate the effect) can be attributed to the action of endorphins in the brain. So, in simpler terms, placebo effect is an endogenous mechanism of analgesia driven by endorphin action. What are some…

Example 1 – Cristiano Ronaldo Football strike: Bones and Joints: Kicking a football uses all of the bones and joints in your lower body. The tarsals, metatarsals and phalanges of your foot provide the contact surface that strikes the ball. The tibia and tarsals form your ankle joint, which must stay slightly flexed but rigid when you kick so that no power is lost. Your knee joint, consisting of the tibia and femur, extends as your thigh muscles contract and your hip, which is made up of your…

Chronic depression, also referred to as dysthymia or chronic depression is a mood disorder. Chronic depression is defined any feelings of hopelessness and unhappiness that persists for more than two weeks, and it is different from psychotic depression. With psychotic depression, the illness is accompanied by some form of psychosis, such as delusions, detachment from reality, and hallucinations. In addition to emotional disturbances, chronic depression is also like to sensory disturbances, such…

symptoms, and depression. Dopamine agonists have a variety of names: Parlodel, Cabaser, Mirapexin, Requip, Neupro, etc. They act like dopamine to stimulate the nerve cells and a few side effects are: headaches, constipation, nausea, and drowsiness. Apomorphine is a group that is taken via injection. This drug is used if someone with PD does not respond to oral tablets or patches. There can be side effects of nausea and sickness. The fourth group is the glutamate agonists. It is common that these…

was passed by the FDA in 2010). Lurasidone has a high to moderate affinity for multiple binding sites that are exclusive to this drug though similar to other atypical antipsychotics (5HT7, 5HT1A, and α-2C in addition to high affinity as a partial agonist to 5HT1A) (Deckersbach, 2015). The highest affinity for an antagonistic effect lurasidone contains is a distinctive trait and works on the 5HT7 which presents an interesting array of noted therapeutic possibilities. Not only is lurasidone an…

addicts in mental institutes was not working and something needed to change. Methadone, one of the medications used for MAT, was developed as a research project to respond to this heroin epidemic (Joseph, Stanfliff and Langrod). Methadone is a full agonist; it activates the opioid receptors and…

Parkinson’s disease is a slowly developing neurological disorder in which cells are lost in the brain. The fact that cells are lost makes it a progressive disorder of the nervous system. The National Parkinson Foundation states on their website that the most substantial area of degeneration is the Substantia Nigra in the brain which produces dopamine. Before symptoms occur, roughly 60%-80% of the neurons in the Substantia Nigra have diminished. Dopamine allows for communication between neurons…

information in the type of way that can affect people of our society. Sometimes information and news only occurs when an African American Individuals commit a crime. I believe the media can manipulate information and influence society to generalized agonist certain…