Agonist

This journal article examines the protein-adjuvant co encapsulation of particle is used for vaccine delivery. In recent decades, vaccination is effective interventions in terms of preventing and eradicate disease. Vaccine delivery is gaining more and more attention. This journal gives audience four main points. The first one co-encapsulation of protein and pep-tide derived adjuvants in vaccine particles. The second point is two different methods for separate two type encapsulated substances, the…

depression and potential for kratom abuse as opposed to the effects of misusing opioids (Henningfield, Fant & Wang, 2018). It seems that kratom is a mimic of an opioid on account of its almost identical opioid properties “recently referred to as biased agonists” (Henningfield, Fant & Wang, 2018). When the early 2000s came long, kratom has been “increasingly used” as a natural medicine to treat “mood and quality of life and as substitutes for prescriptions and illicit opioids form managing pain…

In the hypothalamus, there is a neural circuit known as the melanocortin system, which includes two populations of neuron located in the arcuate nucleus, that express the proopiomelanocortin propeptide (POMC) and agouti-related protein (AgRP) (Roseberry, Stuhrman et al. 2015). POMC propeptide is the precursor to the melanocyte-stimulating hormones (α, β, and γ-MSH) (Roseberry, Stuhrman et al. 2015). The melanocortin system plays a significant role in controlling feeding and body weight…

Introduction Lorazepam is a kind of benzodiazepine in terms of pharmacological class, It is also an anxiolytic drug in terms of the therapeutic class.It is mainly used to treat anxiety and insomnia for adults.Since anxiety and isomnia is getting more common nowadays, It is nesseary to be introduced to more people.In this article, you will know more about the clinical trial ,the pharmacology ,and the pharmacokinetics of Lorazepam. Disscussion of a clinical trial for Lorazepam Lorazepam has a…

types of hormone therapy include hormonal contraceptives, Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists, progestin therapy, and Danazol. Hormonal contraceptives include birth control pills, patches, and vaginal rings. These contraceptives help control the hormones that cause the buildup of endometrial tissue. According to mayoclinic.org Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists block the production of ovarian-stimulating hormones, lowering estrogen levels…

All ambulances must also carry the medication Epi. This drug must be carried in both adult and pediatric dosages. The chemical name of Epi is Epinephrine. Its chemical equation is C9H13NO3. The molecular weight of Epinephrine is 183.207 g/mol. Epinephrine has a hydrogen bond donor count of four, a hydrogen bond acceptor count of four, and a rotatable bond count of three (14). Epinephrine is given intramuscularly via auto injector. The dose is 0.3mg for adults and 0.15mg for pediatric…

et al., researchers were interested in determining whether sex differences exist for the cannabinoid modulation of appetite, body temperature, and neurotransmission at POMC synapses. The drugs that were used in this experiment were a 1 mg/kg s.c. agonist CB1 receptor WIN 55,212-2, a 3 mg/kg s.c. antagonist AM251, and a 1 ml/kg s.c. vehicle. This study had two parts to it with one focusing on the behavioral aspects of the animals and the other on the biological aspects. Behavioral…

There are many types of artificial sweeteners on the market found in numerous low calorie foods or diet drinks. Unlike sugar, these artificial sweeteners have no actual caloric value, and don't affect blood glucose levels as much for diabetics as regular sugar would. Artificial sweeteners are man-made, sometimes derived from sugars occurring naturally in nature. Splenda, a commonly used brand, is made of the artificial sugar sucralose while equal is made of the artificial sugar aspartame. These…

Performance Enhancing Drugs. One of the most popular topics in all of sports, particularly baseball. It’s been around the game for the past few decades, and possibly even before that. When you think of Performance Enhancing Drugs, or PED’s for short, you think of a drug that are considered illegal, narcotic, or even dangerous, depending on how much you use. This stuff is no joke. These drugs are also considered an abusive substance, meaning you can do more harm to other people, other than…

Acetylcholine Research Forums The following members Li Jiang, Lorna Role, and David Talmage were able to develop a method towards controlling mice memories, by manipulating the neurotransmitter called acetylcholine. 1.) Purpose: As of this article Science Daily, “previous research has suggested that cholinergic input to the amygdala appears to strengthen emotional memories.” Memory that could be tuned, providing dreadful memories or dementia can be erased furthermore gone from the human’s…