Agonist

very active, same with your arms and wrist. The wrist is constantly flexing and extending to rhythmically bounce the ball up and down the court. The elbow joint is responsible for flexing and extending your arm, it works with the bicep and tricep (agonist and antagonist). When nearing the hoop you have to transition into the stepping phase. During the stepping phase the focus moves to the legs; quads, gastrocnemius, knee joints, hip joints. In this phase the gastrocnemius and quads are engaged…

Antiemetics Overview: Antiemetics are used for nausea and to prevent vomiting and also used for motion sickness. These drugs can be bought over the counter. (OTC) Action: Dimenhydrenate or Dramamine is an antihistamine. It should be taken one hour before travelling, and will prevent motion sickness. The antihistamine is available in children’s liquid formula and in a Less Drowsy Formula that may have fewer sedative side effects. Meclizine hydrochloride (Bonine) treats vomiting and dizziness…

brain and spinal cord. Multiple brain regions, pathways, and chemical mediators are involved in this modulation of pain. One type of powerful mediator involved in pain modulation are opioids. Endogenous opioid peptides, as well as exogenous opioid agonists, bind and activate opioid receptors. Activated opioid receptors directly inhibit ON cells and also inhibit GABAergic interneurons which inhibit OFF cells, thus indirectly disinhibiting OFF cells. The net result of opioid receptor activation is…

Epidural analgesia is commonly used to provide pain relief during labor. To convert epidural analgesia in labor for emergency cesarean section, a strong solution of local anesthetic is required aiming to achieve rapid and good quality of epidural anesthesia. Different solutions of local anesthetic are used for this reason. The optimum choice of local anaesthetic solution for achieving rapid and reliable epidural anaesthesia for caesarean section is still not clarified [1]. The solution used is…

Names: Generic: modafinil, Trade name in New Zealand: MODAVIGIL® (MIMS 2015). Drug class: Central nervous stimulants (Wake- promoting agents) (Ballon and Feifel, 2006) Formulation: Modavigil ® is formulated as modafinil white to off-white, crystalline powder in tablet form. It is available in tablets containing 100mg of modafinil. Excipients in the tablet are: lactose, strach, pregelatinised maize, maicrocrystaline cellulose, croscarmellose sodium, providone and magnesium stearate (Medsafe,…

the incidence of ED (El Batawi, 2015)‌. Another sedative, dexmedetomidine, is a novel drug that is being added to our anesthesia department's armamentarium this week for trial in our pediatric population. Dexmedetomidine is an alpha-2 adrenergic agonist that is eight times more selective for the alpha-2 receptor than is clonidine. This medication possesses many qualities that make it favorable in the outpatient setting: anxiolysis, analgesia, preservation of respiration, and reduced…

Over the past decade, the number of prescription drug issues has dramatically risen. Prescription opiates are being widely abused often leading to an addiction or becoming a gateway to harder, more dangerous substances. Unfortunately, more often than not, doctors are unknowingly enabling drug abusers and addicts instead of helping to aid them. Prescription opiates are often addictive but seem to be the only choice at the time when a patient is in pain. We need to continue research of…

contaminants in the cannabis 5. It is also possible that the accumulation of increasing levels cannabis metabolites leads to paradoxical vomiting seen with long term use6 .Cannabidiol is one of the metabolite which is a partial agonist at CB receptors thus acting as an agonist in lower concentration and antagonist at higher levels 6.Cannabigerol is a metabolite of cannabis which is antagonist of cannabis at the receptors .These metabolites tend to accumulate in chronic users and hence there…

surgery (2). Jaron states, puberty blockers are used to “prevent the development of secondary sexual characteristics that may later be difficult to alter, such as Adam’s apple or larger breast” (2). This is achieved with gonadotropin releasing hormone agonists” (2). Adolescences are allowed to receive this treatment when they have reached the “Tanner 2 stage” of puberty (2). If adolescents develop physical characteristics of their gender, then they would have to resort to surgical procedures to…

Sleeping is a natural part of our daily life. It is a behavior that is displayed every day and is necessary for us to function. To be able to rest efficiently an animal, be it a human or another mammal, needs to fall asleep in a matter of seconds or minutes; but since a sleeping animals are more vulnerable to predation, it also needs to wake easily in case of threat. Those requirements show how well regulated the sleep-wake regulation has to be. Historically, sleep studies have been done by a…