Adverse drug reaction

Examining Substitution Reactions of Several Alcohol-Containing Compounds Several Experiments were performed using substitutions reactions with hydrogen halides. These results and favor methods or pathways for the several alcohols were observed and will be discussed. Introduction for all the material Scheme 1. Substitution of 3-(m-tolyl)propan-1-ol to form 1-(3-bromopropyl )-3-methylbenzene. Aromatic materials used in this reaction has high boiling point thus the reaction was heated…

Overview: A fair test is conducted to determine how much bicarb soda is needed to extinguish a tea-light candle when mixed with vinegar. When bicarb soda and vinegar are mixed together a chemical reaction is made thus extinguishing a lit candle, the candle is blown out as bicarb soda and vinegar creates carbon dioxide. A candle needs oxygen to burn, however when carbon dioxide is poured above the flame the candle will quickly be put out, as carbon dioxide is a heavier gas. Aim: To…

cations. Lead was identified in Part A, barium was identified in Part B and different flame colors were observed with various metal chloride solutions in Part C. Formula unit, total ionic, and net ionic equations were written for the confirmation reactions for both lead and barium. If this experiment was repeated, barium could be confirmed by the yellow precipitate BaCrO4 after confirming that the solution was clear and any excess contaminants were removed through heating. Step 13 could be…

In our Chemistry class, we the students had performed an experiment that involves with a soda can, being crushed. Going step by step, our group simply placed small amounts of water into the soda can. Then we placed the soda can on a hot surface which allowed the water to boil. Once the water was boiling, our group witnessed the steam coming out from the opening on top of the soda can and one of us picked up the soda can with beaker tongs. We quickly submerged it into cold water and the instant…

To improve the yield of the ester the reaction should be heated using a high temperature. This would favour the formation of the products in this reaction, as the formation of an ester (esterification) is an endothermic reaction. Thus use of a high temperature will push the equilibrium to the right hand side, and a larger yield of the ester will be produced. To improve the yield of the Ester the reaction mixture could be refluxed for longer period of time so that more reactants are converted…

Solventless Reactions: The Aldol Reaction CH204-01 Fadwa Mekkaoui Introduction: An aldol reaction is the formation of a new carbon-carbon bond by the addition of a nucleophile to an electron deficient carbon. The reaction is favorable in Green Chemistry. It demonstrates green principles such as using no solvent and having a high atom economy. In the lab a mixed aldol reaction was performed to synthesize an unsaturated ketone from and aldehyde and ketone. By using an aldehyde, that doesn’t…

look like Figure 6. Even though there seems to be some error occurring, it looks as if pyrazole acted as a competitive inhibitor. This means pyrazole bind to the active site, where normally the substrate would bind, on AdhP. When this happens the reaction is prevented, but can be overcome by adding more substrate. This type of inhibition can be seen in Figure 7. Figure 3 then allowed us to create a Dixon Plot as seen in Figure 4. This Figure showed the largest source of error and actually had a…

Experiment 9 “proteins” and the purpose of the lab is to become familiar with some reactions of proteins and some of the tests used to detect proteins. The activities for this experiment includes the following: selected reactions of proteins will be carried out, several tests for proteins will be performed including: biuret test, xanthoproteic test, and millon test. This lab is broken down into two sections: precipitation (coagulation) of egg albumin and color tests for proteins. For the first…

As the temperature increases, the rate of reaction increases until it has reached the optimum temperature above 37°C where the temperature is very high then the reaction rate will decrease. In the data table shown above, there is a similar pattern from increasing the temperature will increase the rate of reaction and as the temperature slowly increases to a certain point then the reaction rate will decrease. When the temperature increase above 37°C, then denature will occur. Also, the…

The extraction lab began with a .517g mixture of benzoic acid, p-nitroaniline, and azobenzene charged in a 125 mL Erlenmeyer flask mixed with 50 mL of Et2O. Once dissolved, the mixture is transferred the mixture into separatory funnel and begin acid extraction. 15 mL of 3 M HCl is added to the separatory funnel and inverted until a phase boundary is present. An additional 15 mL of 3 M HCl was then added and inverted again. The aqueous layer was removed through the separatory funnel and placed…