Adrenergic receptor

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    349) Ventolin: binds to beta2-adrenergic receptors in airway smooth muscle, leading to activation of adenyl cyclase and increased levels of cyclic-3’, 5’ (cAMP), resulting in decreased intracellular calcium that relaxes smooth muscle airways and bronchodilation (Vallerand & Sanoski, 2017, p…

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    Hypertension is a heterogeneous disorder that may result either from a specific cause (secondary hypertension) or from an underlying pathophysiologic mechanism of unknown etiology (primary or essential hypertension). Secondary hypertension accounts for fewer than 10% of cases, and most of these are caused by chronic kidney disease or renovascular disease. Other conditions causing secondary hypertension include pheochromocytoma, Cushing’s syndrome, hyperthyroidism, hyperparathyroidism, primary…

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    Knee Arthroscopy Essay

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    periph-eral nerve blocks and intra-articular injections aiming at reach-ing the ideal technique for postoperative pain control [2]. Many studies were done using different intra-articular agents as local anesthetics, opioids, ketamine, NSAIDS and a2-adrenergic agonists for prevention and treatment of pain after knee surgeries [3]. Dexmedetomidine is a potent and highly selective a2-adrenoreceptor agonist. It has sedative-hypnotic, anxiolytic, analgesic, anesthetic and sympatholytic effects…

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    Haloperidol and Quetiapine In modern medicine, there are two main groups of antipsychotic medicine such as, conventional antipsychotics (1st generation antipsychotics) and atypical antipsychotics (2nd generation antipsychotics). Haloperidol is a conventional antipsychotic which is used to treat schizophrenia and some other forms of psychosis. Haloperidol was developed in the late 1950s by company Janssen, and approved by the U.S. Food and Drug Administration (FDA) in 1967. (David A. Williams )…

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    1. The name of the drug The generic name of the drug that is the theme of this assessment is Metoprolol succinate. The trade names this drug is known as in New Zealand is Betaloc CR and AFT-Metoprolol CR (AFT-Pharmaceuticals Ltd, 2009); AstraZeneca Limited, 2014). 2. General classification of given drug This drug is an antihypertensive medication and a beta1-selective beta-blocker (AstraZeneca Limited, 2014). 3. Indication of use and purpose of given drug Jack is taking Metoprolol succinate…

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    Tizanidine is a central acting alpha-2-adrenergic receptor agonist which selectively binds and stimulate alpha-2 receptors which subsequently reduces spasticity by inhibiting the firing of interneurons, decreasing the release of excitatory neurotransmitters from their presynaptic terminals and reduces the excitability of the postsynaptic…

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    Ventricular Pump Theory

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    Adrenaline in the bloodstream achieves its effects on heart rate by stimulating the adrenergic receptors on cells throughout the heart tissue. Epinephrine 's binding to these receptors triggers a number of metabolic changes. High levels of epinephrine causes contraction of the smooth muscle that lines most arterioles. The way in which adrenaline acts on the sinoatrial node to accelerate…

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    Salbutamol Assignment

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    Pharmacology 1 Major Assignment Salbutamol The chemical name of salbutamol is 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(t-butylamino)-ethanol sulphate, chemical structure is (C13H21NO3)2 • H2SO4 and molecular weight is 576.7g/mol Generic Name: albuterol Commonly used brand name(s): Available doses and dosage forms: Oral salbutamol: Adults and Children over 12 years: Usual starting dosage of salbutamol is 2mg or 4 mg 3 or 4 times a day. A dosage exceeding 4 milligrams of salbutamol 4 times…

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    decreased amount of dopamine receptors, due to an initial blockade, and a decreased performance from the dopamine receptor D2 (Benzer, 256). With the initial decrease performance in the dopamine receptors, there is an adverse reaction with glutamate (Benzer, 257). Glutamate is released more frequently causing catonia subsequently, causing neurotoxicity and…

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    Batawi, 2015)‌. Another sedative, dexmedetomidine, is a novel drug that is being added to our anesthesia department's armamentarium this week for trial in our pediatric population. Dexmedetomidine is an alpha-2 adrenergic agonist that is eight times more selective for the alpha-2 receptor than is clonidine. This medication possesses many qualities that make it favorable in the outpatient setting: anxiolysis, analgesia, preservation of respiration, and reduced incidence of ED following…

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