on olanzapine medication demonstrated a substantial increase in their weight gain, cholesterol levels, and HbA1c compared to SUs on other medications (Newcomer, 2007). SGAs induced weight gain is a result of blockade of some receptors such as serotonin and adrenergic receptors in the central nervous system, which in turn enhances appetite, increases insulin…
The longer I spend studying chemistry and biology, the more I find patterns and overlaps between the two disciplines. As I’ve matured in my studies, I have found the boundaries between the sciences to blur, which has led to my desire to do biochemistry. The course encompasses several science disciplines from biophysics and bioengineering to cellular biology and organic chemistry and looks at these from an analytical and quantitative standpoint. The diversity and interdisciplinary nature of…
Beta blockers are the first line drug choice when treating angina related to CAD. Beta blockers decrease cardiac oxygen demand, by blocking beta receptors in the heart, decreasing heart rate and contractibility, reducing peripheral resistance and after load. Slowing heart rate increases diastolic fill time, increasing the amount of time blood flows throughout myocardial vessels. When taken with nitroglycerin, extra benefits include blunting reflex tachycardia. Dosage starts out low and slowly…
Albuterol (also known as Salbutamol) is a medication indicated for the treatment of both asthma and chronic obstructive pulmonary disease (COPD). This agent works by activating 훽2-adrenergic receptors in the lungs, causing bronchodilation and improving airway patency. In the acute care setting, albuterol is often given via nebulization.1,2 The tablet formulation of albuterol exists as well. However, with albuterol having a low systemic bioavailability, ordering albuterol in its tablet form is…
Asthma Asthma is a respiratory tract disease characterized by spasms of the airway tube that can affect individuals. According to Huether and McCance (2012) well over 34 million adult and children were diagnosed with asthma by health care providers. Although, it is more prevalent during childhood. The purpose of this paper is to discuss the pathophysiology of chronic and acute asthma disorders, implications of genetics on Asthma, as well as diagnosis and treatment.…
The invention relates to formulation of Ketorolac Tromethamine and Phenylephrine Hydrochloride immediate release tablet having less disintegration time. HPLC method was developed and validated for determination of content of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. UV spectrophotometric method was developed and validated to study drug release profile of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. Background:…
causes an increase in the demand of myocardial oxygen. It is through the mediation of α-adrenergic stimulation that increases the individual’s heart rate and blood pressure which in turn, causes the increased demand of myocardial oxygen. These effects are created by the stimulation of the sympathetic nervous system, the stimulation of the central sympathetic outflow and the increased sensitivity of the adrenergic nerve endings to norepinephrine. Stimulation of the sympathetic nervous system is…
therapy can be used alongside CBT to treat negative symptoms. For example, risperidone rebalances dopamine and serotonin levels in the patient to improve behaviour, mood, and thought. It blocks dopamine type 2, serotonin type 2, and alpha 2 adrenergic receptors on nerves, but its exact mechanism is unknown (MedicineNet). This can prevent excessive activity of dopamine, which is associated with schizophrenia. Even more, the clinician should emphasize the importance of medication adherence to…
Discuss the albuterol prescription-be sure to include: brand/generic names, safe dosage, pharmacodynamics, the purpose of the medication, side effects, important nursing considerations and teaching points. Albuterol is an adrenergic bronchodilator. Albuterol is the generic name while Accuneb, Proair HFA, Proventil HFA, Ventolin HFA and VoSpire ER are the brand names. The safe dosage is different depending on the route and the age. For a by mouth form, aged twelve or older,…
NEURO CASE STUDY Y.W. is a 23-year-old male student from Thailand studying electrical engineering at the university. He was ejected from a moving vehicle, which was traveling at 70 mph. His injuries include a severe closed head injury with an occipital hematoma, bilateral wrist fractures, and a right pneumothorax. 1. Define the term primary head injury and describe the mechanism of injury for the student in this case study (how it occurs). (4 points) A primary injury is the initial…