Adenosine receptor

This method was used to generate a value of the flow per min. Afterwards, saline, acetylcholine, adenosine, and nitroglycerin were administered. Maximal flow- dependent coronary vasodilation was calculated by taking the differences in the target-vessel diameter by the tip of the catheter after adenosine was administered. Coronary blood-flow reserve was calculated by taking the ratio of blood-flow velocity of patient at rest to mean peak-coronary blood-flow…

different families, and can have different function depending where they are found in the body. TRPM2 channel is part of a family called transient receptor channel (TRP) [4], and it can be found in many different part of the body, but we will be concentrating on it in the pancreatic β-cell. This channel can be activated by different molecules such as adenosine diphosphate ribose (ADPR) and many others, and through these molecules secret insulin. On the other hand this channel can lead to…

Do you drink energy drinks? Energy drinks are misleading and can cause serious side effects to your body. Many people who consume energy drinks don't even realize how unhealthy those beverages are. I`m here today to give our society factual information on how they can be harmful to your body. How do energy drinks give your body energy? Everyone loves the pump up feeling that the beverages give you, but no one knows how they actually give you energy. Energy drinks consume of sugar and caffeine,…

To understand the effects of agonists and competitive antagonists the receptors involved must be identified first. There are 2 major groups of receptors present in rat ileum, the first being 5-hydroxytryptamine (5-HT) receptors and the second, muscarinic acetylcholine receptors (mAChR) – and of these two groups there are certain subtypes in the ileum contributing to its tone, motility, secretion and blood flow. The 5-HT receptor subtypes most prevalent in the rat ileum were, 5-HT2A, 5-HT2B,…

The receptor opens and conducts Ca2+ in the cytosol which then bind to the membrane channel Ryanodine receptor (RyR) (Silverthorn, 2007). RyR leaks out Ca2+ from the sarcoplasmic reticulum (SR), which induces a calcium spark (Silverthorn, 2007). Calcium binds to troponin, whose affinity to actin is now higher than tropomyosin, the molecule covering the binding site of actin (Silverthorn, 2007). Adenosine-Diphoshate-bound myosin heads now bind to the active…

1. A salivary gland is stimulated by its parasympathetic nerve. a) Describe the organization of the parasympathetic division of the autonomic nervous system The autonomic nervous system (ANS) is a part of the peripheral nervous system that largely acts involuntarily. It consists of nerves in cardiac muscle, smooth muscle, exocrine and endocrine glands. The main visceral activities are temperature regulation, digestion, blood pressure and genitourinary function. The second main division of the…

on the receptor by the enzyme striatal-enriched tyrosine phosphatase (STEP). Once activated, the mGluR is able to activate a tumor-necrosis factor-α-converting enzyme (TACE). The stimulation of TACE will act to cleave the intramembrane protein, neuronal pentraxin receptor. When the protein is cleaved, the extracellular portion is able to stimulate the aggregation of AMPA receptors on the cell surface and help facilitate endocytosis (Lüscher & Huber, 2010). This decrease of AMPA receptors on the…

Caffeine continues to grow in consumption, even though there just is not enough data to justify its growing use. Are we promoting the use and addiction of the new “cocaine”? 85% of American consume at least one drink containing caffeine (Mitchell, D. C., & Knight, C. A. 2014, January). Some of the drinks where we find caffeine is alarming. Caffeine is added to fruit juice, flavored water, sports drinks, to name a few. Sources used included the USDA Food and Nutrient Database for Dietary Studies…

It is my dream and ambition to find the cure for indomitable forms of cancer, by first building my knowledge and skills and then utilizing these towards the larger purpose. While pursuing my Master’s degree, I realized that mere acquisition of information was not sufficient for me and that I wanted a deep insight in my area of interest. Several factors over the past years have contributed towards the goal. My achievements and credentials give me the confidence that I will be able to perform as…

Opioid antagonists are used to strengthen the receptors and transmitters in the basal ganglia and ensure for its effectiveness. Opioid agents offer defense against cell degeneration to the neuronal cells. Other agents protect the dopamine neurons and the retina. A new surgery that is being conducted requires…