Adaptive immune system

COMPONENTS OF EARLY AND LATE IMMUNE RESPONSE IN INFECTIONS Early immune response refers to innate immunity, which is the first line of defense. Innate immunity is a non specific defense mechanism that comes into play immediately or within hours of an antigen’s appearance in the body. These mechanisms include physical barriers for example skin, chemicals in the blood and immune system cells that fight off foreign cells in the body. The innate immune response is activated by chemical properties of the antigen. Late immune response refers to adaptive immunity, which is an antigen specific immune response. The adaptive immune response is more complex that the innate. The antigen first must be processed and recognized. Once an antigen has been recognized,…

The immune system is made up of different parts that are constantly protecting the body from disease-causing microorganisms known as pathogens. By keeping out these infectious pathogens out of the body or destroying the pathogens that do enter the body, the immune system is a complex network of cells and organs that protect the body from infection. The primary immune response is the response that is activated when the body is first exposed to an antigen, resulting in the activation of…

All humans are designed with two types of immunity; innate and adaptive. The innate immune system can distinguish between different classes of pathogens and recruit the most effective form of adaptive immune response to eliminate them. Adaptive responses are a response that the body adapts to certain injuries or insults. Innate responses are non-specific to the insult. Unlike innate immune responses, the adaptive responses are highly specific to the particular pathogen that induced them (Alberts…

immunity means defenses against any pathogen. Adaptive immunity means there’s resistance to a specific pathogen. Innate immunity is also known as nonspecific immunity. It uses the body’s own immune system for defense. Skin that is unbroken or intact is the body’s first line of defense against pathogens. The body’s own natural microbiota or flora is a secondary defense system. Our body’s second line of defense against pathogens is natural, killer cells, phagocytic whole blood cells and fever. The…

Because there are many antigens that enter the body through the gastrointestinal tract, there must be a method by which the immune system is suppressed in order to prevent potentially harmful immune responses resulting from encountering these antigens. It is thought that intraepithelial lymphocytes (IELs) regulate innate and adaptive immune responses, and because there is one IEL per ten intestinal epithelial cells, suppression of the immune system occurs frequently in the gut – in particular,…

Toll like receptors (TLRs) are a class of proteins, which play an important role in the innate immune system. They are usually single, they usually span the entire membrane and are expressed on sentinel cells such as dendritic cells and macrophages, which recognize structurally conserved molecules derived from microbes. When the microbe breaches the physical barriers of the body like skin or intestinal mucosa, the TLRs recognize them and initiate an immune response. The TLRs include TLR1, TLR2,…

The first thing that happens when the influenza virus infects the host cell, is initiating innate immunity. Innate immunity involves phagocytes binding to the pathogen using its pattern recognition receptors, such as toll-like receptors (TLRs), which binds to the pathogen-associated molecular patterns (PAMPs) that are present on pathogen. After binding to its cell surface, it starts ingesting the pathogen using either phagocytosis or macropinocytosis, and destructs the pathogen either by…

pathogenic proteins from innate proteins. Specific gene variants of HLA-DQA1/HLA-DQB1 (HLA-DQ2 or HLA-DQ8), trigger the immune system when exposed to gliadin protein, a derivative of gluten, and cause inflammation in the small intestines. HLA-DQ2 or HLA-DQ8 have been found in almost all genetically tested CD individuals, with HLA-DQ2 being much more prevalent (NLM, 2016). If someone tests negative for HLA-DQ2 and HLA-DQ8 during a diagnostic biopsy for CD, they most like do not have the disease…

entry; (2) attach itself to a host cell and (3) evade the body’s defense mechanisms long enough to produce harmful changes. In this research paper, I will discuss the differences between innate and adaptive immunity along with the chemical and physical factors that are involve in these immunities. It is easy to cluster the structures, cells, and chemicals that act against pathogens into two main lines of defense, each of which overlaps and reinforce each other. The first line of defense is…

The host immune response is important in maintaining the health of periodontal tissues. The presence of pathogens in periodontal pockets will activate innate and adaptive immune responses in an attempt to clear the pathogenic threat as well as promote tissue homeostasis. However, the persistent presence of pathogens can cause the continuous activation of innate and adaptive immune responses; which in turn causes inappropriate inflammatory mediator (cytokine, chemokine, antimicrobial proteins…