Acyl chloride

Nucleophilic Acyl Substitution: The Synthesis of Esters Razon, Valjean Paulo Mella Rico, Fatima Sarah Rogel Institute of Chemistry, University of the Philippines, Diliman, Quezon City 1101 Philippines…

The reaction involves arenes and acyl chlorides or anhydrides. Interestingly, the reduction of acylation products can produce alkylation products. In this study, the chemists were interested in developing a new method of oxazolidine-4,5 to 3, -Aryl-3,4-dihydroisoquinolines. Researchers felt…

paper. Following the addition of 3 mL diethyl ether, the Separatory Funnel could be utilized in order to separate the organic and aqueous layers of the solution. The same funnel process was performed after the addition of 3 mL of saturated Sodium Chloride solution to the previously isolated organic layer. Once separated, sodium sulfate could be used to dry the product followed by the addition of 1-2 drops of product to 1 mL of diethyl ether, yielding the desired…

created protein-lipid-detergent complexes. Proteinase K is added to digest proteins and any nucleases that might damage the DNA (Peant and LaPointe, 2004). RNase is added to avoid impurities from RNA. The addition of the chaotropic salt guanidinium chloride present in the lysis buffer helps the DNA adhere to the silica surface of the DNeasy Mini spin column by forming a cationic bridge that connects the DNA and silica gel (Yang et. al., 1998). It also denatures lipids and proteins, preventing…

1- Introduction Benzosuberone based compounds are important classes of biologically active compounds that attracted a great deal of interest in the medicinal chemistry due to their potent biological activities and wide range of pharmaceutical applications [1-6]. Several publications recorded that some of benzosuberone derivatives possess antipyretic, anti-inflammatory, antimicrobial, antiulcer and antitumor activities [1-6]. As an indication for the importance of the benzosuberone based…

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

ANEQ 305 Muscles in Racehorses There are many ways in which researchers can examine muscles of thoroughbred racehorses. They can look at the amount of, and different types of muscle fibers found in thoroughbreds, the muscles ability to adapt to high intensive exercise, the effects from changing the inclination the horse is exercising on, and if age and gender affect the way the muscles react. The thoroughbred horse stems back to a founder stallion that makes up 95% paternal and 9 to 10…

A small burette funnel was filled with column packing solvent at mobile phase, high boiling petroleum, in this case hexane (and then 10%acetone hexane mixture), and Alumina as stationary phase. When adding the sand and the alumina they have to be first mixed with the hexanes in order not to disturb the column. The Lycopene is Red- Orange and more attracted to alumina due to its high degree of Unsaturation, which can be expected to be eluted after Yellow-Orange Carotene pigments. And the other…

Chapter: Soil, Water and Air Pollution 1. Introduction: Definitions of soil, water and air pollution; sources and types of soil, water and air pollution, soil and water pollution status in India With rapid increase and development in industrial and agricultural sectors along with population explosion, huge amount of organic and inorganic waste is released in environment and causing serious threats to environment and agro-ecosystem. This procedure can bring about a danger in the human wellbeing.…

Its derivatives, acyl halides, anhydrides, esters, amides and nitriles, are used in making target products such as flavoring agents, internal plasticizers, pesticides, dyes, textile treatment agents, fungicides, and pharmaceuticals through further reactions of substitution…