Acute toxicity

Beauty over Pain: Getting Rid of Animal Testing “The question is not, can they reason, nor, can they talk. But, can they suffer?” -Jeremy Bentham. By a show of hands, how many of you would cause your pet intentional pain? Would you prod them, lock them up, or inject them with possibly toxic products? That is what most reactions would be. Well, it turns out you may be using one or more animal tested products a day without knowing. Today’s society will do just about anything to get rid of basic…

6. RESULTS AND DISCUSSION All the results generated from the present study are represented in the respective tables. The powdered gum of Acacia arabica was subjected to preliminary organoleptic evaluation. The scanty availability of information on this plant facilitates the study on it. The attempt is made to study the Pharmacognostical, phytochemical and pharmacological activities of gum of the plant. The study was divided into three major parts viz. • Pharmacognostical studies •…

Caffeine metabolism and excretion in premature infants is limited due to their immature hepatic enzyme, P450 1A2 (CYP1A2), which is involved in caffeine biotransformation to theophylline; and due to immature renal function. Therefore, it is acceptable to say that caffeine elimination is slower in preterm neonates than in full term neonates, due to the fact that preterm neonates have a lower glomerular filtration rate(GFR). The GFR increases rapidly during the first 2 weeks of life and then…

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

1. What is the most likely diagnosis of the underlying disease in this patient (5 marks)? Follicular Lymphoma. 2. Describe the process of autologous transplantation for the treatment of this patient’s disease. (5 marks). Stem cells are removed from patient and stored in a freezer. Patient will then receive high dose chemotherapy with or without radiotherapy to get rid of circulating tumor cells in the blood. The removed stem cells are transfused, replacing the destroyed tissue and…

Journal of Endocrinology 2015 (2015): 312305. PMC. Web. 16 May 2018. [5] Negro, Roberto. “Selenium and Thyroid Autoimmunity.” Biologics : Targets & Therapy 2.2 (2008): 265–273. Print. [6] MacFarquhar JK, Broussard DL, Melstrom P, et al. Acute Selenium Toxicity Associated With a Dietary Supplement. Arch Intern Med. 2010;170(3):256–261. doi:10.1001/archinternmed.2009.495 [7] Dolan, Laurie C., Ray A. Matulka, and George A. Burdock. “Naturally Occurring Food Toxins.” Toxins 2.9 (2010):…

continued after delivery, it can reduce the rate of relapse from 50%, down to 10%, and lithium may be a better choice for you than other mood stabilizers. You can help reduce the risks from lithium by: • Limiting your salt intake to prevent lithium toxicity. • Staying hydrated. • Monitoring thyroid hormone levels and kidney function in infants that are breastfeeding. • Monitoring lithium levels in both you and your child, (medical experts suggest every 6 - 8…

Acute infection is the first stage, which is when the person comes into contact with HIV. Typically two to four weeks after a person comes in contact with the virus flu like symptoms being to present themselves, although not everybody that gets HIV will…

routinely good if intervention is initiated early, with the primary goal return of euglycemia using supplemental dextrose infusion and octreotide to reduce further insulin secretion. Metformin-associated lactic acidosis (MALA) can occur with both acute and chronic metformin exposure. While MALA is not common, its associated rates of morbidity and mortality can be high. Secondary to MALA, the patient may experience changes in the central nervous system, cardiovascular collapse, renal failure, and…

7a. What risk factors does M.P. have to develop Reye’s syndrome? (1 pt) M.P. risk factors of developing Reye's syndrome include giving OTC Alka-Seltzer that contains aspirin. In most cases of chicken pox happen in children between the ages of 5 to 9 years of age. Reye's syndrome is often in children between 4 to 12 years of age. Taking the Alka-Seltzer because it contains aspirin, increases the risk of Reye's syndrome. 7b. What symptoms would indicate M.P. was developing Reye’s syndrome?…