test embryos for the presence of genetic sequence linked to a variety of conditions and characteristics. In order to keep Kate alive, Anna was brought into this world via PGD to be a perfect genetic match for her sister who suffered from acute promyelocytic leukemia. She was conceived as a bone marrow match for Kate. This test was used to create Kate sister Anna to try to save Kate. Anna’s umbilical cord was harvested when she was born to help save Kate. 2. What is the practical dilemma and…
In the movie My Sister’s Keeper, Sara and Brian Breslin make the decision to conceive their daughter Ana through in vitro to donate compatible organs to their daughter Kate who suffers from acute promyelocytic leukemia. The ethical issue in this movie is the decision Ana’s parents made to go through with genetic pre-implementation with the specific goal of saving their older daughter Kate. The moral agent, Ana, faces moral obligations to save her sister by serving as an organ bank. She is at the…
Orphan drugs under normal market circumstances would not be produced by the pharmaceutical companies due to the expense incurred and potentiality of financial loss due to low levels of sales. Orphan drugs are created to treat, prevent, and diagnose rare diseases with a prevalence of less than 5 in 10,000 per community. An Orphan medicinal product must show an enhanced therapeutic benefit over existing treatments against rare life threatening or debilitating diseases. An orphan drug is not a rare…
INTRODUCTION Lovastatin is a statin drug that decreases the total cholesterol level in patients diagnosed with hypercholesterolemia. The drug aims to prevent serious cardiovascular diseases such as heart attack due to blockage of arteries. Lovastatin acts as a competitive inhibitor for the HMG-CoA reductase enzyme in catalyzing the conversion of HMG-CoA to mevalonate, (Alberts, 1998). The drug is also hydrolyzes in vivo to active form β-hydroxyl acid, (Katz, 2005) and was recently researched on…
element that presents metal and non-metal properties. As exists in the world in inorganic and organic forms. It is used for the production of herbicides, pesticides and wood preservatives, and recently has been used for treatment against acute promyelocytic leukemia (Sun et al., 2014). Although used to treat this cancer, As is a known carcinogen as…