Orphan drugs under normal market circumstances would not be produced by the pharmaceutical companies due to the expense incurred and potentiality of financial loss due to low levels of sales. Orphan drugs are created to treat, prevent, and diagnose rare diseases with a prevalence of less than 5 in 10,000 per community. An Orphan medicinal product must show an enhanced therapeutic benefit over existing treatments against rare life threatening or debilitating diseases. An orphan drug is not a rare…
How much life do you lose from smoking? You lose about 14.5 years of the average 78.8 which comes out to about 18.4% of the average life span. they have ingredients like Cadmium Benzene which are linked to some cancers. Even though it can be used as a medication, cigarettes should be illegal because there are many side effects to using the product and many toxic chemicals go into the product. Medicine would be the last thing you think when it comes to cigarettes ,but it is true that they have a…
Timothy Ray Brown was diagnosed with HIV in 1995 and he soon began the antiretroviral therapy, because he was able to control the virus with medications he never presented any illnesses associated with AIDS. When he was later diagnosed with acute myeloid leukemia he was given chemotherapy to treat the cancer, the reaction of the chemo mixed with his antiretroviral drugs had toxic effects and so he stopped taking the HIV medicine. This too also had a negative affect and he was put back on to the…
INTRO Polycythemia Vera (PV) is a slow growing blood cancer that causes the bone marrow to over produce blood cells. It is a chronic progressive Myeloproliferative Neoplasm (MPN) primarily characterized by an elevation of red blood cells ("Polycythemia Vera (PV)," 2014). SIGNS AND SYMPTOMS Most people with PV don’t experience symptoms, but those who do will undergo headache, weakness, excessive sweating, painful swelling of one joint (often the big toe), difficulty breathing when you lie down,…
Few things are as devastating as disease or terminal illness. Several diseases have made an appearance or re-emergence over the last couple of decades – HIV being among the most prevalent and devastating. HIV, or the human immunodeficiency virus, “is a chronic infectious disease passed from one person to another through blood-to-blood or sexual contact” (Hoeger, Hoeger, Hoeger, & Fawson, 2015). HIV was originally formed in chimpanzees in Central Africa, and spread to humans through infected…
Tobacco smoke contains more than 7,000 chemicals, some of which contribute to tobacco dependence.[1] However, nicotine is the major chemical component in tobacco that is responsible for addiction.[2] Nicotine can be readily absorbed through the mucosa of the mouth, nose, and lungs. It can also be readily absorbed through the skin.[2] With tobacco smoking, nicotine reaches the brain in 10 seconds.[1] Once in the brain, nicotine stimulates the release of the neurotransmitter dopamine, which is…
The end of World War II brought rise to the tobacco industry and essentially introduced Americans to tobacco use. More predominately, Americans’ cigarette consumption was on a rapid incline. A significant amount of Americans were smoking, yet only about 40% knew the health risks of smoking cigarettes (Graham, 2012). Americans remained ill-informed until the 1960’s when healthcare professionals began shining a negative light on the health consequences of smoking. On January 11, 1964, the Surgeon…
Tobacco use is prevalent and widespread, it may seem like the amount of smokers are on the decline but the numbers are astonishing. Tobacco use kills up to half of its users (Tobacco). “Every time a person lights up a cigarette he or she releases 4,000 chemicals into the air and at least sixty nine of them are known to cause cancer” (Bast). Research has proven cigarette smoke can cause cancer, and inhaling secondhand smoke can be just as harmful as smoking itself. Secondhand smoke is a key…
This may cause accumulation of errors rapidly in the cell and its progeny. * Those in signaling (endocrine) machinery of the cell. This leads transmission of the error signals to nearby healthy cells as well. * Those that allow the cells to migrate and disrupt more healthy cells away from the primary site of origin. * Those that make the cell immortal so that the abnormal cell refuses to die. Hormonal changes Notable among these are changes in the female hormone levels estrogen. Excess…
To fulfill Carolyn’s homework assignment. JK feels healthy due to running 2 miles every other day and eating a low fat/high fiber diet three times a day. JK desires to maintain his BP around 120/80, keep his LDL below 129, remain committed to his low fat/high fiber diet and running 2 miles every other day. JK believes that God has a plan for his life but it’s still JK’s responsibility to take preventative measure in caring for his body. He stays up to date on all his vaccinations and…