Acute lymphoblastic leukemia

be treated by the use of embryonic stem cells. Many people today who have health issues that can be cured by stem cells would be grateful for the opportunity given to them by the medical advancement. In a similar situation, people with Acute Lymphoblastic Leukemia would most likely not have the chance to survive if it were not for bone marrow transplants. In my brothers case, the bone marrow transplant was the last chance of hope. Just like others with different cancers, trauma injuries, and…

Research shows genetic factors play a significant role in causing a variety of pediatric cancers. This paper will provide research and evidence linking genetic factors associated with frequently diagnosed childhood cancers. Childhood acute lymphoblastic leukemia (ALL) is one of the most frequently diagnosed cancers in children today. “ALL is considered to be a condition that arises…

she needs family, friends, teachers and health care personnel to help him or her through it. Recovery becomes doubly difficult when any of these people fails in their roles. The case study Emily is a young girl who has just been diagnosed with leukemia. She is the daughter of Teresa. Teresa has been through a tumultuous life and is at present a single mother. She has two other children. At present, she has a man with whom she lives but he has been reluctant to co-parent with her. She has…

Recently, a child in the United Kingdom was treated and cured of refractory relapsed acute B lymphoblastic leukemia. The procedure was made possible by careful use of genetically engineered T cells. The T cells were used in combination with enzymes known as transcription activator- like effector nucleases, or TALENs, to stop genes from the donor T cells…

Since I can remember, I have wanted to be a nurse. Not just a regular Register Nurse but a Pediatrician Oncology Nurse. That is why I have decided to write this paper on how children with cancer use religion in their lives at such a critical time, how their parents use spirituality to cope, and spiritual distress. In the article, Seminars in Oncology Nursing, it states “Spiritual integrity is a basic human need, the perceived spirit within each individual as a driving force giving mean to life…

Orphan drugs under normal market circumstances would not be produced by the pharmaceutical companies due to the expense incurred and potentiality of financial loss due to low levels of sales. Orphan drugs are created to treat, prevent, and diagnose rare diseases with a prevalence of less than 5 in 10,000 per community. An Orphan medicinal product must show an enhanced therapeutic benefit over existing treatments against rare life threatening or debilitating diseases. An orphan drug is not a rare…

This may cause accumulation of errors rapidly in the cell and its progeny. * Those in signaling (endocrine) machinery of the cell. This leads transmission of the error signals to nearby healthy cells as well. * Those that allow the cells to migrate and disrupt more healthy cells away from the primary site of origin. * Those that make the cell immortal so that the abnormal cell refuses to die. Hormonal changes Notable among these are changes in the female hormone levels estrogen. Excess…

Historically, children have been excluded from research for decades to protect them from any risk associated with the drug. In an attempt to protect children, these subjects have been the victims of off-label drug use. Children have been given prescription or over-the-counter medication to treat or cure their illnesses ultimately causing them harm than good. The off-label drugs have little or no data available on children. Since the data is available on adults, assumption is made that the drug…

Vincristine is the primary treatment for acute lymphoblastic leukemia (ALL) in children. Common toxicities include peripheral and autonomic neuropathies, which can be life threatening. Vincristine is metabolized extensively by CYP450 3A and its PK has a significant inter-individual variation. In addition to chemotherapy treatment, children are given antifungals for prophylaxis of infections. Itraconazole, voriconazole and fluconazole are commonly used agents. The azole family is an inhibitor of…

In mid-December, a measles outbreak started at Disneyland, in Orange County, California. That outbreak has now infected one hundred people in California, and twenty-five people in other states across America. With this outbreak and others that occurred recently, there were over six hundred measles cases in 2014. Before this outbreak, the average number of measles cases in the United States annually was approximately 100 (Corum). In 2014, California also had the highest amount of whooping cough…