Cover Letter: I chose the muscle cell because I was interested in it. I wanted to learn how muscle growth happens and how muscles get damaged. I also wanted to learn what a muscle looks like and what types of muscles there are. I wanted to learn how it is built too. Introduction: “Muscles packed with mitochondria give meat a darker color (referred to as dark meat) than muscles with fewer mitochondria (referred to as white meat).” Its body system, malfunction and disease, and…
A single frog leg that was severed from the body at the hip joint was dissected to isolate and expose the gastrocnemius muscle. The gastrocnemius muscle was first separated from the tibiofibula bone, but left attached to the knee and the Achilles tendon. A 15 cm long piece of strong thread was tied tightly around the Achilles tendon of the heel of the frog for later attachment of the muscle to the force transducer equipment. The Achilles tendon below the tied string was then severed and the…
Myosin are a large superfamily of motor molecule which is move along cytoskeletal filaments and interact with actin filaments. That movement requires huge amount of hydrolysis ATP molecules to change the conformation. The genomic analysis thirteen different members of the myosin gene. In addition, the most present myosin type in all eukaryotic cells are: myosin I and myosin II. On the other hand, the less present type of myosin is myosin V. Also, myosin can be divided to two class; conventional…
Calcium will begin to bind to troponin. The troponin moves tropomyosin out of the way since it blocks the actin’s active site. Next, actin uses myosin-ATPase to break down ATP to ADP and phosphate so that the myosin heads can attach to the actin. The same myosin head will then form a bridge on the active site of the actin filament in order to That bridge pulls in actin and pushes it over…
decrease in length (e.x. lifting weights) it is called a concentric contraction. When muscles increase in length (e.x. doing pushups) it is called an eccentric reaction. There are two proteins responsible for muscle contractions: Actin and Myosin. The interaction of Actin filaments gliding over Myosin filaments is what causes the shape change in muscle cells. The physical process of muscles contracting happens rapidly.…
Muscle fibres. There are three types of muscle fibres; type 1, type 2a and type 2b. A. Type 1: These fibres are slow twitch or slow oxidative fibres and are red due to the presence of large volumes of myoglobin. They contract slowly but can contract repeatedly over long periods. These fibres would be suitable for an athlete such as a marathon runner because this is an endurance sporting event that requires you to use aerobic energy which relies on oxygen from the blood for the supply of energy.…
slippage of myosin fibers on the actin fibers. For this, the head of the myosin binds to the troponin site of the actin filament. Then, an ATP molecule will bind to myosin to separate actin and myosin and thus allow its attachment to the neighboring troponin site due to hydrolysis of ATP in ADP + Pi. This creates a slippage of myosin fibers on the actin fibers and allows for muscle contraction. However, one molecule: tropomyosin binds to the troponin sites present on the actin filaments and thus…
In order for a skeletal muscle to contract, it has to first be stimulated by a nerve (Harrison, 2006). The muscles contract by a process known as the sliding filament theory. The structures involved in this process are myofibril, sarcomere, actin and myosin (Jackson,…
calcium ions into the cytoplasm of the muscle cell called the sarcoplasm. Once in the sarcoplasm, calcium ions can easily bind to the protein troponin located on an actin filament, which causes a shift in the thread-like protein tropomyosin. This ultimately exposes the active sites on the actin filament, allowing the contractile filaments actin and myosin to form a…
skeleton (Sherwood, 2010, p257). Skeletal muscles have a striated structures of alternating light and dark bands (Sherwood, 2010, p258). A bands, which are dark and primarily composed of myosin, and I bands, that are light are primarily composed of actin filaments (Sherwood, 2010, p258). The interaction of these bands is responsible for muscle contraction. Muscle cells,…