Actin

glomangiosarcoma is more difficult to diagnose because of the absence of benign glomus tumor histology, and can be easily confused with other sarcomas. Immunostaining is helpful in the diagnosis as tumor cells are typically positive for smooth muscle actin and vimentin but negative for epithelial, vascular and neural markers (i.e. desmin, cytokeratin, S100, chromogranin, and neurofilament)…

anti-inflammatory, hepatoprotective, anti-proliferative activites has been studied in vitro; however its effects on osteoclast differentiation have not been demonstrated. In this study, CTXA was found to suppress RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption in RAW 264.7 cell lines and mouse bone marrow monocytes (BMMs). CTXA significantly inhibited the JNK/mitogen-activated protein kinase (MAPK) signaling pathway without affecting ERK and p38 signaling in…

Ranging from 50 to 200nm in diameter and reaching up to 100µm in length, TNTs are thin actin-containing bridges that allow for communication between cells, transmitting both cytosolic and membrane bound molecules, organelles and even pathogens (Marzo 2012). TNTs are implicated in transmission of prion disease by transferring in vitro endogenous…

designers and he brought happiness and laughter to the movie, when a character or the chorus sung usually created a brighter scene. My favorite actor in this movie as Steve Martin as Orin Scrivello the dentist. I think he did an excellent job in actin in this movie, he had a good charisma and even though he was the and evil character he still manages to bring a good sense of humor to the movie. The main reason I was…

temperature. Each of the membranes were again washed with 0.05% TBST for 10 min (three to five times), and 2 mL of ECL™ Prime Western Blotting Detection Reagent (Biorad) was added to detect the peroxidase present. Types of antibodies Preparation ratio Β-actin 1:2000 Bax 1:1000 p53 1:1000 Cytochrome c 1:500 Caspase 8 1:2000 Table 1. The list of antibodies…

although our body recruits different muscle fibers for different activities. The first muscle fiber to be recruited are slow twitch fibers, are also known as Type I. “Slow twitch muscle fibers are the smallest in diameter, contain the least amount of actin and myosin, and allow…

For this lab report the class goal was to figure out if our dominate hand is stronger than our non-dominate hand. There are a few factors that come into play when measuring this, the first thing that is important to know is what a muscle is and how it works. According to Medicine net a muscle is “the tissue of the body which primarily functions as a source of power.” A muscle is also used for movement and keeping body parts in their right positions. There are 3 different types of muscles,…

with the elicited contractile forces. Changes in muscle length are directly correlated to changes in sarcomere length; the length of the muscle dictates the amount of overlap in the sarcomere. It is documented that the ideal overlap of the myosin and actin filaments is at the ‘optimum resting length’ (Winter, 2010). At this distance, the maximum force of contraction from a maximal stimulus will be produced; with further modulations in length promoting an overall decrease in contractile…

Not being able to understand someone leads to Autistic children avoiding social interaction, however this leads to negative effects as well. A lack of social interaction does not give children the socialization that they need to develop. Children with Autism have trouble understanding society and their peers. This impacts their cognitive abilities and brain development. The book “Freaks, Geeks, and Asperger’s Syndrome” is written by Luke Jackson, a thirteen year old boy who has Asperger’s…

Muscle Cramps As a recent victim of severe muscle cramps, I decided to take up the matter as the topic of my extra credit project. Muscle cramps are muscle spasms elongated for indefinite periods of time. Muscles contract involuntarily and forcibly, resulting in mild to intense pain that can last anywhere from seconds to over fifteen minutes. Muscle cramps can appear distorted or feel firmer than its normal, relaxed state. Muscle cramps have the ability to affect any skeletal muscle, whether…