Acinetobacter baumannii

Introduction: Resistance to antibiotics is an ongoing concern of the pharmaceutical industry. The limited number of antibiotics in the market to treat Gram negative bacteria made their resistance an issue that is being addressed worldwide. The isolation of colistin from Bacillus polymyxa var. colistinus in Japan in 1949 and the introduction of colistin into the market in 1959 as its inactive prodrug colistin methanesulfonate (CMS) were significant milestones in the treatment of this type of…

related to age and co morbidities than the presence of the multiresistant organism per se. So the panel unanimously decided not include HCAP in the HAP/VAP guideline update this year. Use of antibiogram: The guideline also urges that every hospital and ICU has their own antibiogram tailored to their HAP/VAP population if possible. This was based on their evaluation of some observational studies one of them was done with 229 patients at 4 different institutions which showed the variation in…

Introduction/Review of Literature Introduction Hospital acquired infections (HAI), also known as healthcare associated infections or nosocomial infections, are infections transmitted to patients while in a hospital or other healthcare facility. According to the Centers for Disease Control and Prevention (2015), there were approximately 722,000 patients suffering from hospital acquired infections in the United States in 2011 of whom 75,000 suffered fatalities. Accordingly, hospital acquired…

The purpose of the research was to potentially find a new bacteria that is capable of producing an antibiotic against one or more of the six ESKAPE pathogens (a group of pathogens that are resistant to most if not all current antibiotics). All research protocol was based on the Yale Small World Initiative and the third edition of Microbiology Laboratory Theory & Application. One bacteria from a sample of soil collected (colony #18) was tested for its ability to produce antibiotics against two of…