How Different Drugs Work in the Body at a Molecular Level First, it is important to understand the drug kinetics so as to understand how a drug works. Typically, this is how the drug is introduced to the body, how it reaches the point of action, and how it is removed from the body. The most important stage is absorption, and it highlights how the drug is introduced into the body. It includes intravenous administration, subcutaneous injection, intramuscular injection, oral administration, and…
of Aerobic Reactions by molecules that endure a series of reactions that soon result in pyruvate. Krebs cycle is a central metabolic pathway that is in every aerobic organisms as well as pyruvate molecules converted to 2 carbon compounds known as Acetyl CoA. The purpose is to excerpt electron and creates more ATP. NAD+ is a type of coenzyme found in all living organisms. Just like cargo trucks carbon dioxide is released into the air as carbon is broken…
Discuss the role of acetylcholine on neuromuscular function. Acetylcholine helps muscles move and that allows the body to support itself by the skeletal system. Acetylcholine is made in the cell by acetyl-CoA and then stored in the vesicles. The vesicles is then released into the synaptic cleft and acetylcholine binds to the receptors producing a response. Once that happen, acetylcholinesterase (AChE) enzyme breaks down acetylcholine and the choline…
TOPIC: ECONOMIC IMPORTANCE OF FUNGI Before we discuss the economic importance of fungi let us have a brief study about what fungi really are. Fungi are multicellular, eukaryotic, non-chlorophyllous, living organisms which feed heterotrophically by absorption and have a cell wall made up of fungal cellulose and have a body made up of hyphae called mycelium. In this universe each and everything has its own economic advantages and disadvantages. Let us first study the advantages of fungi…
PHYSICAL PROPERTIES: It has two isomeric forms 1, 2, 3-triazole and 1,2,4-triazol with common molecular formula C2H3N3,and both have 69.06 molecular weight. [2]] 1, 2, 4-triazole derivatives simply exist in solid forms. 3, 4, 5-substituted 1, 2, 4-triazole derivatives melts on thermolysis when heated at high temperature3160C for half an hour. 1, 2, 4-Triazole derivatives are easily soluble in polar solvents and slightly soluble in non-polar solvents. However the solubility in non-polar solvents…
cholesterol concentrations while the excess steroid hormones will lowers plasma cholesterol concentrations (Guyton and Hall, 2006) The process of cholesterol synthesis (image 2) consists of five main stages (King, 2010), among others: 1. Changing Acetyl CoA into…
fluids of the eye (3). Resistance to the drug can occur in large bacterial populations where some of the cells are less permeable to the drug however the more relevant form of resistance occurs when bacteria develop the ability to make chloramphenicol acetyl-transferase. This enzyme is encoded for on a plasmid and acts as a virulence factor…
Maple Syrup Urine Disease (MSUD) is a rare, autosomal recessive metabolic disorder in which the body is unable to process certain amino acids properly. It causes brain damage and progressive nervous system degeneration. MSUD is caused by mutations in three different genes: BCKDHA, BCKDHB and DBT (Warrell, Cox and Firth, 2012). The BCKDHA gene causes MSUD Type Ia due to the mutation in the E1α subunit, BCKDHB causes Type Ib due to the mutation in the E1ᵦ subunit, and DBT causes Type II due to…
The energy currency for almost all living organisms is a compound called ATP, or adenosine tri-phosphate. This compound is made of up one adenine and three phosphate molecules which link together to form a structure like this: Adenosine Notice that the three bonds within this molecule become increasingly longer the farther away the phosphate is from the adenosine. This is to represent the fact that the bonds weaken as the distance between the adenosine and phosphates increases. This is…
1) Alcaligenes faecalis is a Gram-negative coccobacilli that is motile, oxidase positive, catalase positive, non-spore-forming, non-fermenting, slow growing, and citrate positive obligate aerobe (Mahon et al., 2014) (Sachdeva et al., 1963). Its colony morphology is flat, thin, and rough with irregular edging (Mahon et al., 2014) and the flagella varies between the usual shape versus the curly structure, however, both shapes do not exist on the same individual bacteria (Leifson, 1960). The…