Acetic anhydride

The components of Alka Seltzer come together to form a pain reliever and antacid formulation. Aspirin is classified as a Nonsteroidal Anti-inflammatory Drug and has the function of a pain-killer, helping to reduce inflammation, fever and pain within the body by reducing the production of a substance called prostaglandins which are “hormone-like substances” (Drugs 2017) that regulate the inflammation and cause the bodies pains and headaches.(Merck Animal Health) The Sodium Hydrogen Carbonate…

Identifying Unknown Esters Produced by Fischer Esterification Introduction This procedure was performed in order to prepare an ester using an unknown alcohol and unknown acid via Fischer Esterification. Then to identify this unknown ester using gas chromatography. Esters are a derivative of carboxylic acids. In the Fischer approach, an acid is used in order to allow the esterification to occur. Gas chromatography separates compounds by their elution time. Data and Results The compound in the…

Aim: To use a neutralization reaction to propel a model rocket. Hypothesis: That the neutralization reaction between the bicarbonate of soda and the vinegar will produce a gas, which build up enough pressure to launch the bottle rocket. Materials: Vinegar, bicarbonate of soda (NaHCO3) Equipment: Plastic Bottle, Wooden Block, Nail, Cork, Duct Tape. Method: 1. Nailed a cork to plank of wood as a base for the rocket. 2. Wrapped tape around cork so that it fitted the neck of the bottle. 3. Put two…

Twenty kids one answer, who will figure it out. Everyone has been given the task to find the mystery mixture. At first they all had different clams. But now it is getting narrowed down. But there are some people that had different opinions. Everyone have been given water, a well tray, and a vial, along with other chemicals. I will explain how the class had gotten answer they did. And how they think it is right. The claim that will be explaining will be citric acid and baking soda. One of the…

Molecules like cyclosporine that are non-ionisable, lipophilic and non-polar are challenging to formulate due to their low solubility and no effect of pH on solubility, and they are also solubilised in non-aqueous solutions composed entirely of organic solvents. The combination of polyoxyethylated castor oil and ethanol that are water miscible surfactants and solvents can be used to solubilise the non-polar active ingredient, cyclosporine. Therefore, the excipients are appropriate for the…

Direct methane activation into chemicals and fuels can be compared to converting lead into gold, as methane is an inert molecule with few methods of selective transformation. Methane is a ubiquitous byproduct with the potential to create more efficient chemical syntheses and replace the current petrochemical feedstocks through less expensive and more readily-available alkanes . C-H bond activation frequently occurs at transition-metal centers , often with high selectivity and trivial conditions.…

Data Calculated from Experiment Solid-Liquid Weight (g) Solid-Liquid % Recovery Liquid-Liquid Weight (g) Liquid-Liquid % Recovery Acid 0.01 20 % 0.028 56 % Phenol 0.011 22 % 0.001 2 % Amine 0.013 26 % 0.005 10 % Neutral 0.03 60 % 0.026 52 % Table 1 shows the data obtained from this experiment of both the solid-liquid extraction (on the left side of the table) and the liquid-liquid extraction method (on the right side of the table). It shows that in the solid-liquid extraction, most of the…

Abstract The primary goal for this laboratory experiment was to synthesize, purify, and identify p-nitroacetanilide using acetanilide as the starting material. To test for the purity and identification of our desired product, we gathered data from: Thin Layer Chromatography (TLC), Melting Point (MP) range, Infrared (IR) spectrum, Gas Chromatography Mass Spectroscopy (GC-MS), and Proton Nuclear Magnetic Resonance (1H NMR). TLC plate indicated the formation of our pure product due to the…

First, 2-aryl-5-methoxy oxazoles were prepared by the method of Wipf’s protocol*) from methyl N-acyl glycine methyl esters in the presence of Et3N in DCE with PPh3 and I2 at room temperature for 19-24hr. These reactions proceeded in mild condition and gave 2x to 80-97% yield by column chromatography. Then, we attempted to apply the method of Friedel–Crafts acylation in order to synthesis of acylated oxazoles from 5-methoxy -2-phenyl oxazole (*). The normal conditions which used Lewis acid…

The aim of this experiment is to carry out a reaction that results in the synthesis of paracetamol. Paracetamol results when 4-aminophenol reacts with acetic anhydride. The impure, crude product will be compared to the final pure product. The percentage yield will be calculated. Paracetamol (acetaminophen) is a pain reliever, a fever reducer and an anti-inflammatory drug so it is used in many other drugs. The exact mechanism of action of it is not known but the scheme of the synthesis of…