disease. Genetic tests are highly accurate but it is not globally applicable due to too different mutations and variability between populations and regions. Biofluid tests rely on sample treatment and copper detection by ICP-MS or Atomic Absorption Spectroscopy, both of which are expensive, time-consuming and not easily acccessible.3 Diagnosis of Wilson’s disease could be considerably simplified by the development of chemoselective copper frameworks that give direct read-outs of copper…
[19] and DNA typing [20], both aiming at the identification of crime victims or suspects/persons-of-interest. However, forensic science methods are beginning to far exceed such applications and often include various analytical methods, such as spectroscopy and electrochemical techniques, have seen tremendous developments. Modern developments are based on multi-disciplinary approaches involving not only physical techniques, but also computational methods. Collection and storage of samples into…
Complexation of Cyclodextrins Cyclodextrins (CDs) are most important carriers because of their semi-natural property as it is produced from a natural material i.e. starch, by simple enzymatic conversion. Solubility and dissolution rate of BCS class II drugs can be improved by addition or by complexation with hydrophilic carriers like cyclodextrins. Cyclodextrins have the capability to form inclusion complexes with the guest molecules i.e. poorly water soluble drugs. The formed inclusion complex…
the reaction of p–[1–(p–hydroxyphenyl) methylcyclohexyl] phenol with methylcyclohexanone, epoxidation with epichlorohydrin followed by addition reaction with acrylic acid. All synthesized compounds were characterized by 1H-NMR, 13C-NMR and FT-IR spectroscopy. Several UV-curable formulated solutions were prepared separately by mixing the prepolymer, BISCHDA (75%), diluent, tri (ethylene glycol) diacrylate (TEGDA) (25%) and different concentrations of a photoinitiator,…
Coulter Counter Method. Schematic Diagram Diagram 1: The basic setup of coulter counter method. Test tube containing conducting fluid placed in the beaker containing same conducting fluid. Orifice in the test tube connect the circuit. Electrodes are placed in beaker and test tube and voltage is applied. Vacuum is applied in the test tube to allow fluid movement from beaker to test tube. Counting circuit will calculate the amount of particle and pulse height analyser will measure the particle…
3. Results and discussion 3.1. Grafting of CNT on the ramie fabric The schematic representation for the mechanism of ramie fiber surface treatments is shown in Fig. 2. For the alkali treatment of ramie fiber, the NaOH reacts with the hydroxyl groups of the ramie fiber as shown in Fig. 2(a). During silane treatment, the hydrolysis of silane takes place initially (Fig. 2(b)) which then reacts with the active hydroxyl functionalities in ramie fiber (Fig. 2(c)). Each silane molecule has three…
INTRODUCTION Background The macrocyclic organic molecules Phthalocyanines (1) which are comparable to the naturally occurring porphyrin (2) ring systems shown in (Figure 1). The porphyrin molecule consists up of four pyrrole subunits which are associated in n-conjugation by methine carbons. 1 2 Figure 1: structures of phthalocyanine and porphyrins molcule The compound…
of Au(III) ions. The sorption of gold ions was quantitative in pH range of 2.0 to 6.0, whereas quantitative desorption occurs instantaneously with 6.0 mL of 1.0 mol L-1 Na2S2O3. The eluted solution was aspirated directly into the flame of atomic absorption spectrometry. The proposed method permitted a large enrichment factor of 105. The precision of the method was ±2.3% (n=8 and C=2.0 µg mL-1) and the limit of detection (3Sbl) was 0.1 ng mL-1. The calibration curve for gold is linear between…
The calibration curve observed in this investigation was the relationship measured between the concentration of the cobalt solution, or CO(NO3)2, and the absorbance of the wavelength. As it was impossible to measure the true standard curve, the data points and subsequent graphs demonstrated the qualitative information collected and the trend of these values. The calibration curve closely resembled a straight line, with only minimal deviations in either direction. This indicated that the…
spectra. Energies in the radio range would need a magnetic field of approximately 0.7 T for resonance. Figure 2 gives us a glimpse of what ESR spectra should look like. On the first diagram we can the first derivative detection of absorption line on the bottom and the absorption is represented by the peaks above and proves that hyperfine interactions have occurred between energy…