Zaman 9-24-07

Front 1

Asthma is a polygenic disorder which results from an initial exposure to an
_____.

Back 1

“allergen”

Front 2

Difficulty breathing results from the type ____ hypersensitivity reaction involving
constriction of respiratory smooth muscles, increased mucous production,
edema and inflammatory cell infiltration.

Back 2

I

Front 3

In chronic cases, airway tissue is ______ with smooth muscle
hypertrophy, basement membrane fibrosis, edema and inflammatory
infiltrate (eosinophilia is significant).

Back 3

“remodeled”

Front 4

______ deviation is responsible for Ig-E isotype response to the “allergen”.

Back 4

Th2

Front 5

____-cells are responsible for driving the asthmatic attack (histamines) as
well as later development of responses (cytokines).

Back 5

Mast

Front 6

Treatment involves identifying “allergens” and use of anti-inflammatory
agents (such as ______,…).

Back 6

antihistamines, bronchodilators

Front 7

Immunotherapy would involve deviating T cell response from Th2 to Th1 to
eliminate _______ of mast cells.

Back 7

“sensitization”