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18 Cards in this Set

  • Front
  • Back
C reactive protein
Pentameric protein found in the blood plasma which rises in response to inflammation- binds to phoshocholine expressed on the surface of dead cells
Low risk c reactive protein
Less than 1.0 mg/dl
High risk
Over 3.0mg/dl
Types of angina
Stable, unstable , prinzmental, nocturnal, microvascular
What is the difference between stable and unstable angina
Stable- chest discomfort on exercise, lasts for a few minutes, relived with gtn

Unstable- occurs at rest, more severe, crescendo pattern with failure to respond to therapy
Acute coronary syndrome- 3 features
Unstable angina, STEMI, NSTEMI
ECG changes on angina
ST depression, t wave inversion, ventricular arrythmia,
Signs and symptoms of angina
Chest pain- retrosternal, which radiates down left arm, palpitations, sense of impending doom, nausea and vomitting
Risk factors
Smoking, diet, diabetes, high cholestrol, hypertension, age 55 over for men
Other medical problems with angina
Hyperthyroidism, anaemia
Diagnosis
Resting ECG, cardiac scintography, echocardiogram, cardiac marker level, MRI
Poor sign on resting ecg
St segment depression is greater than 1 mm
Surgical intervention
Cabg from saphenous vein, angioplasty, internal mammary arterial implantation
Cardiac markers on angina
Ck-mb normal , troponin 1 and troponin t is raised
Treatment pharmo
Nitroglycerin- converted to NO by aldehyde dehydrogenase and is a potent. Vasodilator

B blocker and calcium channel blocker given

Aspirin and statin
Other conditions which can cause chest pain
Pulmonary embolism, aortic
Dissection, pericarditis
What is prognostic measure
Timi
What is timi
Ischemic modified albumin, myloperoxidase, gpbb, troponin