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7 Cards in this Set

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What are the main sources of ATP for muscles?

(1)creatine phosphate




(2) glycogen




(3) oxygen for cellularrespiration in the mitochondria of the fibers.

Which system produces ATP from phophocreatine?




Describe how this is done

- phosphagen system

- phosphagen system

Compareand contrast endurance and resistance training

-resistance training increases strength and muscle fibre size (crosssectional area e.g. myosin and actin).




-endurance exercise increases resistance to fatigue by increasingoxidative capacity – secondary to increased mitochondrial density




-both induce protein synthesis in differing fractions of muscleprotein i.e. myofibrilar vs mitochondrial proteins

Describe how the source of ATP for muscles changes during length of activity

Define fatigue




What is the difference between central and peripheral fatigue?

progressive,though transient, decline in the force- or power-generating capacityof working skeletal muscle




-peripheral fatigue is associated with limitations within in themuscle i.e. accumulation of metabolic products, and the depletion ofphosphagen and its substrates




-central fatigue relates to impaired motivation, neuromusculartransmission, motor unit recruitment and motor cortex activation

Summarize the three systems of ATP production used by muscles

List 2 factors associated with peripheral fatigue

-lactic acid is a byproduct of the reduction of pyruvate (the endproduct of glycolysis). This does not cause fatigue directly, though can inhibit phosphofructokinase (PFK; an important enzyme inglycolysis). It also displace Ca2+ from troponin, hindering muscle contraction, and stimulates painreceptors.




-Oxygen delivery to the periphery may also be limiting as oxidativephosphorylation is dependent upon oxygen, which acts as the finalelectron acceptor in the electron transport chain. If thecardiovascular system fails to deliver sufficient oxygen, then thatbecomes a limiting factor for aerobic metabolism.