Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
|
This FQ does not lose its greater gram negative coverage.
|
Levofloxacin
|
|
|
INhibits DNA gyrase and topoisomerase IV.
|
FQs
Resistance: efflux pumps and altered target site |
|
|
This FQ is only PO, not IV
|
Gemifloxacin
|
|
|
Chelate in blood w/ metallic ions (di and tri) not mono
|
FQs (also tetracyclines, but not this lecture)
|
|
|
These 2 FQs do NOT tx UTIs
|
Gemifloxacin and moxifloxacin
|
|
|
Only 3rd gen FQ that has pseudomonal coverage
|
Levofloxacin
|
|
|
2nd gen FQ
|
Ciprofloxacin
covers Pseudomonal and atypicals |
|
|
metabolized by CYP1A2
|
Ciprofloxacin
|
|
|
Tx of anerobes below the diaphragm except actinomyces
|
Metronidazole
pt complains of metallic taste |
|
|
DOC for anthrax
|
Ciprofloxacin
|
|
|
UTI, MRSA, PCP prophylaxis, TOXO prophylaxi
|
TMP-SX
IV, PO |
|
|
Steven johnson rash
|
TMP-SX (more the SX than the TMP)
|
|
|
inhibits conversion of PABA to dihydrofolic acid
|
Sulfonamides (sulfamethoxazole)
|
|
|
inhibits converstion of dihydrofolic acid to THF acid
|
Trimethoprim
|
|
|
TB drug that does NOT cause hepatotoxicity
|
Ethambutol
SE: decreased visual acuity and change in Red / green discrimination |
|
|
inhibits mycolic acid synthesis
|
Isoniazid (IV and PO)
|
|
|
SE: hepatotoxicity, peripheral neuropathy
|
isoniazid (give B6 w/ this drug)
|
|
|
monotherapy for bacterial meningitis- combo therapy everywhere else
|
Rifampin (IV, PO)
|
|
|
SE: orange colored bodily fluids + hepatotoxicity
|
Rifampin
|
|
|
CYP450 Inducer that is used to tx TB
|
Rifampin
|
|
|
Only first line TB drug that is only PO
|
Pyrazinamide
|
|
|
hepatotoxicity + arthralgias
|
pyrazinamide
|
|
|
Second line TB
|
FQ (mox and levo)
Streptomycin- IV/IM amikacin/ Ranamycin- IV/IM Capreomycin- IV/IM cycloserine-PO ethionamide P-aminsalicyclic acid |
