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9 Cards in this Set

  • Front
  • Back
What is the trade name for Alefacept?
Amevive
What is the trade name for Efalizumab?
Raptiva
What are the 2 main "biologic" agents, not TNF-alpha inhibitors?
Alefacept and Efalizumab
This biologic is a recombinant dimeric fusion protein, made from the portion of LFA-3 that binds to CD2 and the Fc portion of IgG
Alefacept (Amevive)
This biologic is recombinant humanized IgG monoclonal antibody that binds to the human subunit CD11a in LFA-1
Efalizumab (Rapitva)
Efalizumab (Raptiva) binds to what subunit in LFA-1?
CD11a subunit
Both biologics, Alefacept (Amevive) and Efalizumab (Raptiva) are manufactured inside of what animal part?
Chinese hamster ovary
Which biologic is a recombinant dimeric fusion protein made up of LFA-3 and Fc IgG?
Alefacept (Amevive)
Which biologic is a recombinant humanized IgG that binds to LFA-1?
Efalixumab (Raptiva)