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43 Cards in this Set

  • Front
  • Back
What is an ALLELE?
Alternative versions of a gene
What is a BASE?
One of the nitrogen-containing side-chain molecules attached to a sugar molecule in the sugar-phosphate backbone of DNA and RNA. The four bases in DNA are adenine (A), thymine (T), guanine (G), and cytosine (C); the four bases in RNA are adenine (A), uracil (U), guanine (G), and cytosine (C); the information in a molecule of DNA and RNA is determined by its sequence of bases
What is a BASE PAIR?
Two nucleotides on complementary strands of DNA that form a pair, linked by hydrogen bonds; the patterns of pairing is adenine (A) with thymine (T) and cytosine (C) with guanine (G); the base-paired arrangement forms the "rungs" of the double-helix structure of DNA
What is BIOTECHNOLOGY?
The modification of organisms, cells, and their molecules for practical benefits
What is a CHROMOSOMAL ABERRATION?
A type of mutation categorized by a change in the overall organization of genes on the chromosomes, such as the deletion of a section of DNA; the moving of a gene from one part of a chromosome to elsewhere on the same chromosome or a different chromosome, or the duplication of a gene, with the new copy inserted elsewhere on the chromosome or on a different chromosome
What is a CHROMOSOME?
A linear or circular strand of DNA on which are found specific sequence of base pairs; the human genome consists of two copies of each 23 unique chromosomes, one from the mother and one from the father
What is a CLONE?
A genetically identical DNA fragment, cell or organism produced by a single cell or organism
What is a CLONE LIBRARY?
A collection of cloned DNA fragments, also known as a gene library
What is CLONING?
The production of genetically identical cells, organisms, or DNA molecules
What is a CODE?
In genetics, the base sequence of a gene
What is a CODON?
Three-base sequence in mRNA that link with complementary tRNA molecules, which are attached to amino acids; a codon with yet another sequence ends the process of assembling a protein from amino acid
What is DEOXYRIBONUCLEIC ACID (DNA)?
A nucleic acid, DNA carries information about the production of particular proteins in the sequences of its nucleotide bases
What is a DNA PROBE?
A short sequence of radioactively tagged single-stranded DNA that contain part of the sequence of the gene of interest, used to locate that gene in a gene library; the probe binds to the complementary base pair on a gene in the library, which is identified by the radioactive tag on the probe
What is a GENE?
The basic unit of heredity; a sequence of DNA nucleotides on a chromosome that carries the information necessary for making a functional product, usually a protein or RNA molecule
What is a GENE LIBRARY?
A collection of cloned DNA fragments, also know as a clone library
What is GENE THERAPY?
A therapy designed to treat or cure a disease by insertion of a functional gene to replace a defective version of the gene
What is GENETIC ENGINEERING?
The manipulation of an organism's genetic material by adding, deleting, or transplanting genes from one organism to another
What is a GENOME?
The full set of DNA present in an individual organism; also can refer to the full set of DNA present in a species
What is a GENOTYPE?
The genes that an organism carries for a particular trait; also, collectively, an organism's genetic composition
What is HUMAN GENOME PROJECT?
A project to decode the three billion base pairs in the human genome and to identify all genes present in it
What is HYBRIDIZATION?
The interbreeding of closely related species
What is an INTRON?
A non-coding region of DNA
What is a MESSENGER RNA (mRNA)?
The ribonucleic acid that "reads" the sequence for a gene in DNA and then moves from the nucleus to the cytoplasm, where the next stage of protein synthesis will take place
What is MUTATION?
An alteration in the base-pair sequence of an individual's DNA; may arise spontaneously or following exposure to a mutagen
What is NUCLEIC ACID?
One of the four types of biological macromolecules, the nucleic acids DNA and RNA store genetic information in unique sequences of nucleotides
What is a NUCLEOTIDE?
A molecule containing a phosphate group, a sugar molecule, and a nitrogen-containing molecule; nucleotides are the individual units that together, in a unique sequence, constitute a nucleic acid
What is a PHENOTYPE?
The manifested structure, function, and behaviors of an individual; the expression of the genotype of an organism
What is a PHYLOGENETIC TREE?
A grouping of organisms in a hierarchical system that reflects the evolutionary history and relatedness of the organisms
What is a PLASMID?
A circular DNA molecule found outside the main chromosome in bacteria
What is POINT MUTATION?
A mutation in which one base pair in DNA is replaced with another or a base pair is either inserted or deleted
What is POLYMERASE CHAIN REACTION (PCR)?
A laboratory technique in which a fragment of DNA can be duplicated repeatedly
What is a PROMOTER SITE?
A part of a DNA molecule that indicates where the sequence of base pairs that makes up a gene begins
What is PROTEIN SYNTHESIS?
The construction of a protein from its constituent amino acids, by the processes of transcription and translation
What is RECOMBINANT DNA TECHNOLOGY?
Technology that depends on the combination of two or more sources of DNA into a product; an example is the production of human insulin from fast-dividing transgenic E. coli bacteria in which has been inserted the human DNA sequence that codes for the production of insulin
What are RESTRICTION ENZYMES?
Enzymes that recognize and bind to different specific sequences of four to eight bases in DNA and cut the DNA at that point; restriction enzymes are important in biotechnology because they permit the cutting of short lengths of DNA, which can be inserted into other chromosomes or otherwise be utilized
What are RIBOSOMAL SUBUNITS?
The two structural parts of a ribosome, which function together to translate mRNA to build a chain of amino acids that will make up of protein
What is a STEM CELL?
Undifferentiated cells that have the ability to develop into any type of cell in the body; this property makes stem cells useful in biotechnology
What is a TRAIT?
Any characteristic or feature of an organism, such as red petal color in a flower
What is TRANSCRIPTION?
The process by which a gene's base sequence is copied to mRNA
What is TRANSFER RNA (tRNA)?
RNA molecules in the cytoplasm that link specific triplet base sequences on mRNA to specific amino acids
What is a TRANSGENIC ORGANISM?
An organism that contains DNA from another species
What is TRANSLATION?
The process by which mRNA, which encodes a gene's base sequence, directs the production of a protein
What is VNTRs (variable number of tandem repeats)?
Regions of repeating sequences of bases in DNA that vary in the number of times the sequence repeats from individual and, in a given individual, between homologues; identification of the number of repeats in several regions can serve as a DNA "fingerprint" unique to an individual