Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
Characteristics of P. aeruginosa
|
- gram negative bacillus
- highly motile with polar flagella - fluorescent under UV light and has colored pigments - smells like grapes or corn chips to some people - ubiquitous in environemtn and can survive on pretty much anything |
|
What are two differenes between P. aeruginosa and enterobacteriaceae?
|
- P aeruginosa is lactose negative on MacConkey and Oxidase +
|
|
Why is p. aeruginosa considered to have intrinsic antibiotic resistance?
|
The cell wall and outer membrane are "impervious" to antibiotics
|
|
Diseases caused by p. aeruginosa
|
- UTIs
- wound infections - sepsis - pneumonia - endocarditis (particularly in immunocompromised patients) - requires a breach in the immune system |
|
What is the relationship between P. aeruginosa and CF?
|
- CF lung selects for P. aeruginosa with increased alginate and decreased digestive enzymes
- leads to chronic inflammation and damage - not a good mucociliary removal of bacteria * PA will preferentially bind to damaged epithelial tissue! |
|
Virulence factors of P. aeruginosa
|
- pili (adherence)
- flagella (spread) - toxins (like LPS) for damage / nutrient acquisition - Exotoxin A - type III secretion system - capsule (undergoes phase variation) |