Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
Chimical nature of cytokines |
Peptides or glycoptns |
|
|
Main source of IFN alpha |
Monocytes and macrophages |
|
|
Main source of IFN beta |
Fibroblasts |
|
|
Cytokines that activate NK |
Type 1 IFN IL2 IL12:++cytotoxic activity IFN gamma |
|
|
In w' step of viral replication the IFN act |
Translation of viral mRNA |
|
|
Proinfalmmatory cytokines |
TNF alpha IL1 IL6 IL8 🔥 |
|
|
IL8 function |
Chemokine |
|
|
W' type of T helper cells inhibited by IL10? |
Th1 |
|
|
W' type of T helper cells are activated by large dose antigen |
Th1 |
|
|
Function and sourse of IL7 |
Sourse (thymic and bone marrow stroma cells) Action:promote devolopment of T and B cells |
|
|
Sourse and function of IL3 |
Sourse : TH1 and TH2 cells Function : promotes formation of blood cells |
|
|
Sourse of IL2 |
Th1 cells |
|
|
Cytokines that ++ expression of MHC 1 |
IFN alpha and beta IFN gamma |
|
|
+cytokines ++ expression of MHC2 |
IFN gamma |
|
|
Sourses of IL4 |
Th2 NK mast cells |
|
|
Cytokine that supress synthesis of proinfalmmatory cytokines |
IL4 |
|
|
Cytokine that play major role in helmenthic infections |
IL5 |
|
|
Cytokines that promote production of IgA |
TGF beta IL5 |
|
|
Cytokine that promote both MHC 1 & MHC2 |
IFN gamma |
|
|
Cytokines Promote growth of B lymphocytes |
IL 4 5 6 |
|
|
TNF and TGF w' one is immunosuppressive |
TGF |
